CRCGN015_MCF10A.WT.HP_24H:G12 Gene Set
Genes
30 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.03967
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
3.75918
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.74958
|
|
EPHB2
|
EPH receptor B2
|
3.08757
|
|
PDIA5
|
protein disulfide isomerase family A, member 5
|
2.85766
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.84023
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.70005
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.53894
|
|
TBPL1
|
TBP-like 1
|
2.43397
|
|
KLHL9
|
kelch-like family member 9
|
2.37509
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.3173
|
|
FPGS
|
folylpolyglutamate synthase
|
2.26134
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.21491
|
|
HDAC3
|
histone deacetylase 3
|
2.11912
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
2.10036
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.00678
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
UFM1
|
ubiquitin-fold modifier 1
|
-3.63237
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.60514
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.49711
|
|
CDC20
|
cell division cycle 20
|
-3.39699
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-3.22179
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-3.13105
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-3.08913
|
|
GDF15
|
growth differentiation factor 15
|
-2.53876
|
|
ELOVL1
|
ELOVL fatty acid elongase 1
|
-2.31251
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-2.21721
|
|
KAT2B
|
K(lysine) acetyltransferase 2B
|
-2.09604
|
|
PFN1
|
profilin 1
|
-2.08644
|
|
EPB42
|
erythrocyte membrane protein band 4.2
|
-2.05412
|
|
ALAS2
|
5'-aminolevulinate synthase 2
|
-2.04367
|
