| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sirolimus 3.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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76 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAMLD1 | mastermind-like domain containing 1 | 4.15139 |
| SCCPDH | saccharopine dehydrogenase (putative) | 4.14665 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 4.10268 |
| TCTN1 | tectonic family member 1 | 4.06879 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 4.03763 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.77731 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.46182 |
| AGR2 | anterior gradient 2 | 3.45986 |
| TBX2 | T-box 2 | 3.39405 |
| WIF1 | WNT inhibitory factor 1 | 3.36684 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 3.16124 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.14076 |
| HMGA2 | high mobility group AT-hook 2 | 3.00076 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.95271 |
| FHL2 | four and a half LIM domains 2 | 2.92229 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.85306 |
| S1PR4 | sphingosine-1-phosphate receptor 4 | 2.83034 |
| MSRA | methionine sulfoxide reductase A | 2.6221 |
| DUSP4 | dual specificity phosphatase 4 | 2.52145 |
| DUSP6 | dual specificity phosphatase 6 | 2.46022 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.45776 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 2.37033 |
| TSPAN4 | tetraspanin 4 | 2.29182 |
| PWP1 | PWP1 homolog (S. cerevisiae) | 2.2419 |
| FOSL1 | FOS-like antigen 1 | 2.23726 |
| COMP | cartilage oligomeric matrix protein | 2.21757 |
| ADH6 | alcohol dehydrogenase 6 (class V) | 2.20983 |
| CYBRD1 | cytochrome b reductase 1 | 2.18074 |
| STK10 | serine/threonine kinase 10 | 2.17099 |
| VAX2 | ventral anterior homeobox 2 | 2.15597 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 2.13564 |
| TMEM50A | transmembrane protein 50A | 2.12424 |
| SCRG1 | stimulator of chondrogenesis 1 | 2.12419 |
| ERLIN1 | ER lipid raft associated 1 | 2.11112 |
| ZW10 | zw10 kinetochore protein | 2.07564 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 2.06703 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 2.05623 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal | 2.04831 |
| INTS13 | integrator complex subunit 13 | 2.01354 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 2.00351 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 2.0014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ALDOC | aldolase C, fructose-bisphosphate | -5.2593 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -4.37173 |
| PRR15L | proline rich 15-like | -3.77678 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -3.54091 |
| INSIG1 | insulin induced gene 1 | -3.37476 |
| TUBA4A | tubulin, alpha 4a | -3.3029 |
| GDF15 | growth differentiation factor 15 | -2.97884 |
| HSPB1 | heat shock 27kDa protein 1 | -2.87508 |
| SH3D19 | SH3 domain containing 19 | -2.87506 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.78934 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.75721 |
| PMM2 | phosphomannomutase 2 | -2.74453 |
| TLK2 | tousled-like kinase 2 | -2.72605 |
| S100A4 | S100 calcium binding protein A4 | -2.71694 |
| S100A8 | S100 calcium binding protein A8 | -2.4759 |
| SESN1 | sestrin 1 | -2.46416 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.39729 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.28974 |
| STAP2 | signal transducing adaptor family member 2 | -2.28963 |
| PPID | peptidylprolyl isomerase D | -2.28497 |
| RNF139 | ring finger protein 139 | -2.23332 |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) | -2.22898 |
| PHACTR4 | phosphatase and actin regulator 4 | -2.22832 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -2.16494 |
| MSMO1 | methylsterol monooxygenase 1 | -2.15139 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.13325 |
| NLRP2B | NLR family pyrin domain containing 2B | -2.12627 |
| MAPK6 | mitogen-activated protein kinase 6 | -2.11455 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -2.10349 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.09342 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | -2.03716 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -2.02452 |
| ABHD4 | abhydrolase domain containing 4 | -2.02387 |
| LBR | lamin B receptor | -2.0228 |
| TUFT1 | tuftelin 1 | -2.0133 |
