CRCGN015_MCF10A.WT.HP_24H:G21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dinitrotoluene 11.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 8.31775
PEX11A peroxisomal biogenesis factor 11 alpha 4.82747
ABHD6 abhydrolase domain containing 6 4.76439
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.24378
MAMLD1 mastermind-like domain containing 1 3.69898
DNASE1L3 deoxyribonuclease I-like 3 2.47722
COL4A1 collagen, type IV, alpha 1 2.45351
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.40055
COMP cartilage oligomeric matrix protein 2.20441
PEG3 paternally expressed 3 2.19064
CXCL12 chemokine (C-X-C motif) ligand 12 2.12474
KRT81 keratin 81, type II 2.04151

decreased expression

Symbol Name Standardized Value
KIF20A kinesin family member 20A -4.19294
PCNA proliferating cell nuclear antigen -4.02954
ACOT9 acyl-CoA thioesterase 9 -3.64093
TRAPPC3 trafficking protein particle complex 3 -3.59687
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.72868
PANK2 pantothenate kinase 2 -2.63244
MRPS15 mitochondrial ribosomal protein S15 -2.61386
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.60856
TMEM230 transmembrane protein 230 -2.43436
NSFL1C NSFL1 (p97) cofactor (p47) -2.42745
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.41084
PLBD1 phospholipase B domain containing 1 -2.26631
MEAF6 MYST/Esa1-associated factor 6 -2.18915
LOC127933115 uncharacterized LOC127933115 -2.17361
SV2C synaptic vesicle glycoprotein 2C -2.15698
APOO apolipoprotein O -2.12202
DUSP6 dual specificity phosphatase 6 -2.03179
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 -2.03
TIMP1 TIMP metallopeptidase inhibitor 1 -2.01839