CRCGN015_MCF10A.WT.HP_24H:G23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4,8-dihydroxy-2-quinolinecarboxylic acid 33.29 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3.41451
LYN LYN proto-oncogene, Src family tyrosine kinase 3.40583
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.12474
EYA1 EYA transcriptional coactivator and phosphatase 1 2.10799

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -4.74212
ATF5 activating transcription factor 5 -3.26574
KIF14 kinesin family member 14 -3.09474
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.54972
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.36366
CD44 CD44 molecule (Indian blood group) -2.32046
MSN moesin -2.27641
ACOT9 acyl-CoA thioesterase 9 -2.16899