CRCGN015_MCF10A.WT.HP_24H:H03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dimethoxybenzidine.2hcl 11.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

41 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 9.46141
RTN2 reticulon 2 4.98152
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.85297
IGHMBP2 immunoglobulin mu binding protein 2 3.23485
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 3.14459
TPD52L2 tumor protein D52-like 2 3.05111
TBXA2R thromboxane A2 receptor 2.43397
ENO3 enolase 3 (beta, muscle) 2.41895
PFKM phosphofructokinase, muscle 2.41758
MRGBP MRG/MORF4L binding protein 2.17715
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.17489
UCKL1 uridine-cytidine kinase 1-like 1 2.13881
FSD1 fibronectin type III and SPRY domain containing 1 2.11941
MYL11 myosin light chain 11 2.10213
SLCO4A1 solute carrier organic anion transporter family, member 4A1 2.09139
SHOX2 short stature homeobox 2 2.05094
TNNT1 troponin T type 1 (skeletal, slow) 2.03805
PDE2A phosphodiesterase 2A, cGMP-stimulated 2.02027

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -5.08076
UFM1 ubiquitin-fold modifier 1 -4.90294
FASTKD5 FAST kinase domains 5 -4.82864
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.70231
NRIP1 nuclear receptor interacting protein 1 -3.83571
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.65393
MSL2 male-specific lethal 2 homolog (Drosophila) -3.07085
ATG3 autophagy related 3 -2.89456
TBCA tubulin folding cofactor A -2.63922
PSENEN presenilin enhancer gamma secretase subunit -2.63686
KRCC1 lysine-rich coiled-coil 1 -2.49641
TCTA T-cell leukemia translocation altered -2.46248
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -2.3976
SERINC5 serine incorporator 5 -2.37553
TBCB tubulin folding cofactor B -2.37136
PAQR6 progestin and adipoQ receptor family member VI -2.35226
CAPNS1 calpain, small subunit 1 -2.31077
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.24258
AK6 adenylate kinase 6 -2.15061
DCBLD2 discoidin, CUB and LCCL domain containing 2 -2.09106
OCLN occludin -2.07628
HMBOX1 homeobox containing 1 -2.06866
TMEM147 transmembrane protein 147 -2.05374