CRCGN015_MCF10A.WT.HP_24H:H05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMBA 33.32 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 3.80476
EPHB2 EPH receptor B2 3.67396
SYNGAP1 synaptic Ras GTPase activating protein 1 3.40923
TLR4 toll-like receptor 4 3.3107
AGR2 anterior gradient 2 3.26523
MOK MOK protein kinase 2.60855
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.57023
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.45641
BLMH bleomycin hydrolase 2.2401
CCNO cyclin O 2.13148
GPATCH8 G patch domain containing 8 2.12072

decreased expression

Symbol Name Standardized Value
BPHL biphenyl hydrolase-like (serine hydrolase) -3.39479
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.33192
PCNA proliferating cell nuclear antigen -3.09805
GADD45B growth arrest and DNA-damage-inducible, beta -2.931
RNF167 ring finger protein 167 -2.87107
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.81313
TSPAN4 tetraspanin 4 -2.71923
ALDOC aldolase C, fructose-bisphosphate -2.68055
XPO7 exportin 7 -2.59541
CORO1A coronin, actin binding protein, 1A -2.57742
TM9SF2 transmembrane 9 superfamily member 2 -2.57133
FAIM Fas apoptotic inhibitory molecule -2.53495
MYNN myoneurin -2.4091
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.33795
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.26454
PDLIM2 PDZ and LIM domain 2 (mystique) -2.18092
C1QBP complement component 1, q subcomponent binding protein -2.12772
ADRB2 adrenoceptor beta 2, surface -2.10057
TMEM230 transmembrane protein 230 -2.04525
EIF5 eukaryotic translation initiation factor 5 -2.04004
NT5DC2 5'-nucleotidase domain containing 2 -2.03101