CRCGN015_MCF10A.WT.HP_24H:H09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminostilbene 11.15 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

48 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZW10 zw10 kinetochore protein 3.61693
SNAP25 synaptosomal-associated protein, 25kDa 3.56602
ABHD4 abhydrolase domain containing 4 3.56494
CHMP6 charged multivesicular body protein 6 3.40541
ADGRE5 adhesion G protein-coupled receptor E5 3.31768
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 3.25752
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.1532
S1PR4 sphingosine-1-phosphate receptor 4 2.96804
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.94281
AGR2 anterior gradient 2 2.87028
FGFR4 fibroblast growth factor receptor 4 2.74291
CIAO3 cytosolic iron-sulfur assembly component 3 2.63302
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.38151
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.31966
ACAA1 acetyl-CoA acyltransferase 1 2.26667
SAC3D1 SAC3 domain containing 1 2.24223
PDLIM1 PDZ and LIM domain 1 2.23543
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.22935
NOTCH1 notch 1 2.20189
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.18748
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.15834
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.15545
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.1225
ERI3 ERI1 exoribonuclease family member 3 2.11308
RNF220 ring finger protein 220 2.07807
SRSF6 serine/arginine-rich splicing factor 6 2.0559
CLEC11A C-type lectin domain family 11, member A 2.03807
NKAPD1 NKAP domain containing 1 2.03401
MTA2 metastasis associated 1 family, member 2 2.00436

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -6.22641
YME1L1 YME1-like 1 ATPase -3.25041
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.11279
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.00904
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.84939
JMJD6 jumonji domain containing 6 -2.79962
NUSAP1 nucleolar and spindle associated protein 1 -2.64416
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.54609
NOP10 NOP10 ribonucleoprotein -2.51741
NDEL1 nudE neurodevelopment protein 1-like 1 -2.42495
FBXO46 F-box protein 46 -2.42252
USP36 ubiquitin specific peptidase 36 -2.35931
HEATR1 HEAT repeat containing 1 -2.29753
HAUS3 HAUS augmin-like complex, subunit 3 -2.29107
RPA3 replication protein A3, 14kDa -2.19608
GDF15 growth differentiation factor 15 -2.16118
ARPP21 cAMP-regulated phosphoprotein, 21kDa -2.09988
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -2.0724
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.02164