CRCGN015_MCF10A.WT.HP_24H:H10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description maleic hydrazide 99.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 3.54508
CHMP6 charged multivesicular body protein 6 3.20892
SSBP2 single-stranded DNA binding protein 2 3.19541
E2F2 E2F transcription factor 2 3.06513
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.9642
ANO10 anoctamin 10 2.81486
SPAG4 sperm associated antigen 4 2.76668
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.65709
TERF2IP telomeric repeat binding factor 2, interacting protein 2.05834
BAMBI BMP and activin membrane-bound inhibitor 2.02439

decreased expression

Symbol Name Standardized Value
HTRA1 HtrA serine peptidase 1 -4.51825
CCDC86 coiled-coil domain containing 86 -4.15648
CYCS cytochrome c, somatic -3.68542
PSRC1 proline/serine-rich coiled-coil 1 -3.24344
ATF5 activating transcription factor 5 -2.95638
COPS7A COP9 signalosome subunit 7A -2.86703
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.84034
ARID4B AT rich interactive domain 4B (RBP1-like) -2.80237
SGK1 serum/glucocorticoid regulated kinase 1 -2.28036