CRCGN015_MCF10A.WT.HP_24H:H11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description maleic hydrazide 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IDE insulin-degrading enzyme 3.92079
ZW10 zw10 kinetochore protein 3.41612
CCL2 chemokine (C-C motif) ligand 2 3.31933
WIF1 WNT inhibitory factor 1 2.68781
HYOU1 hypoxia up-regulated 1 2.6336
MAMLD1 mastermind-like domain containing 1 2.57553
FPGS folylpolyglutamate synthase 2.44401
ARID5B AT rich interactive domain 5B (MRF1-like) 2.43668
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2.13723
STX17 syntaxin 17 2.10437
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.07721
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.00216

decreased expression

Symbol Name Standardized Value
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.70044
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.28114
TES testin LIM domain protein -3.93774
CCDC86 coiled-coil domain containing 86 -3.30395
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.28403
CHMP4B charged multivesicular body protein 4B -3.19268
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.79547
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.74634
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -2.39674
RHOT2 ras homolog family member T2 -2.39625
EEF1AKMT4-ECE2 EEF1AKMT4-ECE2 readthrough -2.27219
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -2.25152
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.24475
STAMBP STAM binding protein -2.16345
CALCB calcitonin-related polypeptide beta -2.13823
MRNIP MRN complex interacting protein -2.1315
MUS81 MUS81 structure-specific endonuclease subunit -2.06906
KCNK12 potassium channel, two pore domain subfamily K, member 12 -2.01225