CRCGN015_MCF10A.WT.HP_24H:H12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description maleic hydrazide 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.30492
RPP38 ribonuclease P/MRP 38kDa subunit 3.36053
SATB1 SATB homeobox 1 2.84066
LYN LYN proto-oncogene, Src family tyrosine kinase 2.79957
TBX2 T-box 2 2.70478
INTS3 integrator complex subunit 3 2.50133
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.49796
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.34486
IGFBP3 insulin-like growth factor binding protein 3 2.24794
WFDC2 WAP four-disulfide core domain 2 2.11995
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 2.10795
SSBP2 single-stranded DNA binding protein 2 2.04248
ATP5F1C ATP synthase F1 subunit gamma 2.0296
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.01861

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -3.82531
MAPK13 mitogen-activated protein kinase 13 -3.06064
TENT4A terminal nucleotidyltransferase 4A -2.88829
SLC35F2 solute carrier family 35, member F2 -2.60877
KDM3A lysine (K)-specific demethylase 3A -2.35706
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.01535