CRCGN015_MCF10A.WT.HP_24H:H13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl methacrylate 98.44 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

41 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.13162
WFS1 Wolfram syndrome 1 (wolframin) 4.07153
STK10 serine/threonine kinase 10 3.35123
MYC v-myc avian myelocytomatosis viral oncogene homolog 3.22495
GPC1 glypican 1 2.97727
RPIA ribose 5-phosphate isomerase A 2.49611
CXCL2 chemokine (C-X-C motif) ligand 2 2.40314
WIF1 WNT inhibitory factor 1 2.26537
FOSL1 FOS-like antigen 1 2.24409
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.18811
HMGA2 high mobility group AT-hook 2 2.09163
OXCT1 3-oxoacid CoA transferase 1 2.06731
SCCPDH saccharopine dehydrogenase (putative) 2.06121
PIH1D1 PIH1 domain containing 1 2.05396
TLCD3A TLC domain containing 3A 2.00252

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -4.4169
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.65432
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.4872
PRR15L proline rich 15-like -2.98227
ARPP21 cAMP-regulated phosphoprotein, 21kDa -2.74617
ALDOC aldolase C, fructose-bisphosphate -2.69155
INSIG1 insulin induced gene 1 -2.67721
EIF5 eukaryotic translation initiation factor 5 -2.64819
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.57157
TUBA4A tubulin, alpha 4a -2.5528
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.47866
BLTP3B bridge-like lipid transfer protein family member 3B -2.44004
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.42545
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.40786
HSPB1 heat shock 27kDa protein 1 -2.31589
S100A4 S100 calcium binding protein A4 -2.30629
BPHL biphenyl hydrolase-like (serine hydrolase) -2.28956
HPCA hippocalcin -2.22562
FRK fyn-related Src family tyrosine kinase -2.20171
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled -2.17114
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -2.15151
RAB30 RAB30, member RAS oncogene family -2.10985
ANO3 anoctamin 3 -2.0864
ANK2 ankyrin 2, neuronal -2.06408
ZSCAN16 zinc finger and SCAN domain containing 16 -2.05709
MINDY1 MINDY lysine 48 deubiquitinase 1 -2.01111