CRCGN015_MCF10A.WT.HP_24H:H15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl methacrylate 10.94 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MEF2C myocyte enhancer factor 2C 4.52826
SNAP25 synaptosomal-associated protein, 25kDa 4.06471
AGR2 anterior gradient 2 3.86881
WIF1 WNT inhibitory factor 1 3.79111
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.7777
PDIA5 protein disulfide isomerase family A, member 5 2.08416
NSG2 neuronal vesicle trafficking associated 2 2.02723

decreased expression

Symbol Name Standardized Value
SLC35F2 solute carrier family 35, member F2 -4.50238
VDAC1 voltage-dependent anion channel 1 -3.51196
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.36457
SNCA synuclein, alpha (non A4 component of amyloid precursor) -3.33925
TENT4A terminal nucleotidyltransferase 4A -3.09412
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.9849
ALAS2 5'-aminolevulinate synthase 2 -2.3145
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -2.24486
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.17559
HBG1 hemoglobin, gamma A -2.08614
NT5DC2 5'-nucleotidase domain containing 2 -2.06065
AHSP alpha hemoglobin stabilizing protein -2.00228