CRCGN015_MCF10A.WT.HP_24H:H19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description estradiol 104.34 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

571 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IL1B interleukin 1, beta 7.40171
CXCL2 chemokine (C-X-C motif) ligand 2 7.1
H2BC12 H2B clustered histone 12 6.10368
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.96935
HMOX1 heme oxygenase 1 5.95198
COMP cartilage oligomeric matrix protein 5.91019
CDPF1 cysteine-rich, DPF motif domain containing 1 5.77868
STXBP1 syntaxin binding protein 1 5.76081
TNIP1 TNFAIP3 interacting protein 1 5.63005
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.47408
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 5.45404
KCTD5 potassium channel tetramerization domain containing 5 5.29003
IER3 immediate early response 3 5.26134
FOSL1 FOS-like antigen 1 4.61581
SYNGAP1 synaptic Ras GTPase activating protein 1 4.46888
CEMIP2 cell migration inducing hyaluronidase 2 4.24344
OXSR1 oxidative stress responsive 1 4.20969
TRIB1 tribbles pseudokinase 1 4.13347
CXCL3 chemokine (C-X-C motif) ligand 3 4.07807
HBEGF heparin-binding EGF-like growth factor 4.05756
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.045
GPER1 G protein-coupled estrogen receptor 1 3.88
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.82586
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.76904
LAMC2 laminin, gamma 2 3.68351
AGR2 anterior gradient 2 3.65686
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3.65302
NRIP1 nuclear receptor interacting protein 1 3.52956
SQSTM1 sequestosome 1 3.52931
IL1A interleukin 1, alpha 3.52515
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.52058
CNPY3 canopy FGF signaling regulator 3 3.52045
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.51727
EGR1 early growth response 1 3.50033
SQOR sulfide quinone oxidoreductase 3.49182
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 3.47829
PTPN1 protein tyrosine phosphatase, non-receptor type 1 3.47143
TUBB6 tubulin, beta 6 class V 3.46764
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 3.46531
WIF1 WNT inhibitory factor 1 3.45777
CCL20 chemokine (C-C motif) ligand 20 3.38838
PRSS3 protease, serine, 3 3.37468
RGS2 regulator of G-protein signaling 2 3.35849
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3.35101
CHIC2 cysteine-rich hydrophobic domain 2 3.30207
MALT1 MALT1 paracaspase 3.2974
LIF leukemia inhibitory factor 3.29254
VAT1 vesicle amine transport 1 3.29253
FHL2 four and a half LIM domains 2 3.24366
CTSL cathepsin L 3.22918
GFPT1 glutamine--fructose-6-phosphate transaminase 1 3.21868
H2BC4 H2B clustered histone 4 3.21635
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 3.18161
SLC35B1 solute carrier family 35, member B1 3.18089
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 3.1153
GARS1 glycyl-tRNA synthetase 1 3.08139
NUCB2 nucleobindin 2 3.07838
EPHA2 EPH receptor A2 3.05835
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.05543
JUN jun proto-oncogene 3.05281
H2BC9 H2B clustered histone 9 3.0305
PLEK2 pleckstrin 2 3.00174
H2AC19 H2A clustered histone 19 2.9842
CALU calumenin 2.97009
H2BC5 H2B clustered histone 5 2.95658
CAVIN3 caveolae associated protein 3 2.94366
G0S2 G0/G1 switch 2 2.93912
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 2.92764
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.92617
DUSP4 dual specificity phosphatase 4 2.92432
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.89356
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.8906
CARS1 cysteinyl-tRNA synthetase 1 2.87877
PRAF2 PRA1 domain family, member 2 2.86807
FSCN1 fascin actin-bundling protein 1 2.86279
SMTN smoothelin 2.84548
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.84545
TERF2IP telomeric repeat binding factor 2, interacting protein 2.8338
MYH9 myosin, heavy chain 9, non-muscle 2.82995
CSNK1E casein kinase 1, epsilon 2.82887
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.82036
CXCL8 chemokine (C-X-C motif) ligand 8 2.80165
ITGA6 integrin, alpha 6 2.80051
DUSP6 dual specificity phosphatase 6 2.79909
CSF3 colony stimulating factor 3 (granulocyte) 2.79439
PLA2G15 phospholipase A2, group XV 2.79355
LRRC36 leucine rich repeat containing 36 2.78298
ALAS1 5'-aminolevulinate synthase 1 2.78105
GLRX glutaredoxin (thioltransferase) 2.78017
H2AC6 H2A clustered histone 6 2.75913
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.75124
TRIM36 tripartite motif containing 36 2.74062
RAP1GAP RAP1 GTPase activating protein 2.72669
DUSP7 dual specificity phosphatase 7 2.72293
CDCP1 CUB domain containing protein 1 2.71839
PDGFA platelet-derived growth factor alpha polypeptide 2.67724
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.6637
ITPRID2 ITPR interacting domain containing 2 2.66366
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.65278
H1-2 H1.2 linker histone, cluster member 2.64325
UGDH UDP-glucose 6-dehydrogenase 2.63461
TIAM1 T-cell lymphoma invasion and metastasis 1 2.63262
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.63026
SH2D2A SH2 domain containing 2A 2.612
COPB1 coatomer protein complex, subunit beta 1 2.60597
SEC31A SEC31 homolog A (S. cerevisiae) 2.58631
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.58309
EHD1 EH-domain containing 1 2.57747
LOC124907782 dual specificity protein phosphatase 22 2.57279
MVP major vault protein 2.56499
TNS4 tensin 4 2.56494
TGFBI transforming growth factor, beta-induced, 68kDa 2.56429
LRRC59 leucine rich repeat containing 59 2.55307
MMP1 matrix metallopeptidase 1 2.54636
LAMB3 laminin, beta 3 2.52056
TICAM1 toll-like receptor adaptor molecule 1 2.51819
SPRY4 sprouty homolog 4 (Drosophila) 2.51669
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.5154
ZBED2 zinc finger, BED-type containing 2 2.49285
MCUR1 mitochondrial calcium uniporter regulator 1 2.49221
CAB39 calcium binding protein 39 2.48277
PTHLH parathyroid hormone-like hormone 2.48235
SH2B3 SH2B adaptor protein 3 2.47821
VEGFC vascular endothelial growth factor C 2.47768
ESYT1 extended synaptotagmin-like protein 1 2.45973
ANKRD40 ankyrin repeat domain 40 2.45549
NRDC nardilysin convertase 2.43554
FOS FBJ murine osteosarcoma viral oncogene homolog 2.43394
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.42798
AXL AXL receptor tyrosine kinase 2.41727
CD83 CD83 molecule 2.41629
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.4125
STX1A syntaxin 1A (brain) 2.40935
ZC2HC1C zinc finger, C2HC-type containing 1C 2.40833
RRAGC Ras-related GTP binding C 2.38762
LUZP1 leucine zipper protein 1 2.37144
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.37092
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.36669
ARF4 ADP-ribosylation factor 4 2.35628
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.35387
GLIPR1 GLI pathogenesis-related 1 2.35245
KRT34 keratin 34, type I 2.35168
GOLT1B golgi transport 1B 2.33653
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.3323
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.33183
TFG TRK-fused gene 2.33006
PLCD1 phospholipase C, delta 1 2.32829
FKBP14 FK506 binding protein 14, 22 kDa 2.32445
P3H1 prolyl 3-hydroxylase 1 2.3195
LARP6 La ribonucleoprotein domain family, member 6 2.31154
DCBLD2 discoidin, CUB and LCCL domain containing 2 2.31068
INPP1 inositol polyphosphate-1-phosphatase 2.30066
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.29737
IER2 immediate early response 2 2.29563
ATF4 activating transcription factor 4 2.29507
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.29441
KLF6 Kruppel-like factor 6 2.29126
STX2 syntaxin 2 2.28124
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.27866
SPRING1 SREBF pathway regulator in golgi 1 2.26444
MFAP2 microfibrillar-associated protein 2 2.25753
ITGAV integrin, alpha V 2.2519
CAVIN1 caveolae associated protein 1 2.24423
GCC1 GRIP and coiled-coil domain containing 1 2.24041
PLEC plectin 2.23778
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.2293
FAT1 FAT atypical cadherin 1 2.22607
ELOVL1 ELOVL fatty acid elongase 1 2.22078
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.22053
H2AC7 H2A clustered histone 7 2.22034
ARMCX3 armadillo repeat containing, X-linked 3 2.21404
PLAU plasminogen activator, urokinase 2.21379
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.20919
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.209
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.20537
ZC3H12A zinc finger CCCH-type containing 12A 2.17728
TMEM40 transmembrane protein 40 2.17563
ERCC1 excision repair cross-complementation group 1 2.16309
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.15448
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.15348
PYCR1 pyrroline-5-carboxylate reductase 1 2.15304
ETV5 ets variant 5 2.15078
KLF10 Kruppel-like factor 10 2.14921
UBA6 ubiquitin-like modifier activating enzyme 6 2.14879
PTPN12 protein tyrosine phosphatase, non-receptor type 12 2.1417
PKP1 plakophilin 1 2.14154
HAS2 hyaluronan synthase 2 2.13708
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.12667
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.12646
PMP22 peripheral myelin protein 22 2.12501
ZMPSTE24 zinc metallopeptidase STE24 2.12473
SPAG9 sperm associated antigen 9 2.12399
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.1182
STX4 syntaxin 4 2.11395
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.11337
JMJD6 jumonji domain containing 6 2.11093
LOC128125822 uncharacterized LOC128125822 2.10775
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.1073
PLK3 polo-like kinase 3 2.10383
HDLBP high density lipoprotein binding protein 2.09685
HRAS Harvey rat sarcoma viral oncogene homolog 2.09192
NECAP1 NECAP endocytosis associated 1 2.08655
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.0792
PTX3 pentraxin 3, long 2.07821
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.07756
COL17A1 collagen, type XVII, alpha 1 2.07735
SOX9 SRY (sex determining region Y)-box 9 2.07598
TGFA transforming growth factor, alpha 2.07384
KLF7 Kruppel-like factor 7 (ubiquitous) 2.07367
LIPG lipase, endothelial 2.07225
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.0664
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.06587
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 2.06189
GRB10 growth factor receptor-bound protein 10 2.05763
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.05447
FICD FIC domain containing 2.05281
SLC35F6 solute carrier family 35, member F6 2.05111
MTSS1 metastasis suppressor 1 2.04763
HMGA2 high mobility group AT-hook 2 2.04604
MAP1B microtubule-associated protein 1B 2.04037
MARCHF3 membrane associated ring-CH-type finger 3 2.03608
MXRA7 matrix-remodelling associated 7 2.02869
UFM1 ubiquitin-fold modifier 1 2.02779
PRKCZ protein kinase C, zeta 2.02755
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.0272
RIC8A RIC8 guanine nucleotide exchange factor A 2.02576
CCN2 cellular communication network factor 2 2.02492
FURIN furin (paired basic amino acid cleaving enzyme) 2.01644
LIMA1 LIM domain and actin binding 1 2.01595
DUSP14 dual specificity phosphatase 14 2.01548
NKX3-2 NK3 homeobox 2 2.01275
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.01051
INHBA inhibin, beta A 2.00305
NTM neurotrimin 2.00289
TUFT1 tuftelin 1 2.00283

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -9.64706
HMG20B high mobility group 20B -6.94828
TOP2A topoisomerase (DNA) II alpha 170kDa -6.78234
PSRC1 proline/serine-rich coiled-coil 1 -6.59261
CDK1 cyclin-dependent kinase 1 -6.3678
CDK4 cyclin-dependent kinase 4 -5.85664
PCCB propionyl CoA carboxylase, beta polypeptide -5.78565
NUSAP1 nucleolar and spindle associated protein 1 -5.69156
DCK deoxycytidine kinase -5.25174
CCNB2 cyclin B2 -4.99861
DDIT4 DNA-damage-inducible transcript 4 -4.83002
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.80843
ADI1 acireductone dioxygenase 1 -4.79766
PRR15L proline rich 15-like -4.78385
MCM3 minichromosome maintenance complex component 3 -4.76479
HADH hydroxyacyl-CoA dehydrogenase -4.63906
ECH1 enoyl CoA hydratase 1, peroxisomal -4.54464
PCNA proliferating cell nuclear antigen -4.36335
TROAP trophinin associated protein -4.08089
KIF11 kinesin family member 11 -4.05763
PSIP1 PC4 and SFRS1 interacting protein 1 -3.98046
CDC25B cell division cycle 25B -3.87502
TP53 tumor protein p53 -3.85439
RPIA ribose 5-phosphate isomerase A -3.83736
SHMT1 serine hydroxymethyltransferase 1 (soluble) -3.83255
AURKB aurora kinase B -3.77352
CCNA2 cyclin A2 -3.73598
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.71277
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.66546
CCNF cyclin F -3.63007
BID BH3 interacting domain death agonist -3.62394
KIF15 kinesin family member 15 -3.61875
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.52797
TSC22D3 TSC22 domain family, member 3 -3.49844
HOXA5 homeobox A5 -3.46065
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.41668
CDC45 cell division cycle 45 -3.39387
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.37831
PRC1 protein regulator of cytokinesis 1 -3.37143
CREG1 cellular repressor of E1A-stimulated genes 1 -3.37067
ACOT2 acyl-CoA thioesterase 2 -3.32476
OIP5 Opa interacting protein 5 -3.29325
PBK PDZ binding kinase -3.28874
SNRPA small nuclear ribonucleoprotein polypeptide A -3.24996
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.24651
RAD51AP1 RAD51 associated protein 1 -3.22098
THEM6 thioesterase superfamily member 6 -3.21577
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.2081
SUOX sulfite oxidase -3.18176
HMGB2 high mobility group box 2 -3.1756
PLK1 polo-like kinase 1 -3.17213
CD58 CD58 molecule -3.13097
RACGAP1 Rac GTPase activating protein 1 -3.12592
PARPBP PARP1 binding protein -3.12096
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.11524
SYNE2 spectrin repeat containing, nuclear envelope 2 -3.10939
NISCH nischarin -3.10856
RPA3 replication protein A3, 14kDa -3.10363
EAPP E2F-associated phosphoprotein -3.08616
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -3.07697
STMN1 stathmin 1 -3.07428
NCAPD3 non-SMC condensin II complex, subunit D3 -3.07375
BAHCC1 BAH domain and coiled-coil containing 1 -3.06539
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.06487
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.0618
FBXO5 F-box protein 5 -3.05393
HEATR1 HEAT repeat containing 1 -3.04556
KIF18B kinesin family member 18B -3.04403
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -3.04215
MCM7 minichromosome maintenance complex component 7 -3.03783
ASF1B anti-silencing function 1B histone chaperone -3.03001
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.0135
COQ6 coenzyme Q6 monooxygenase -3.0064
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.97268
TKT transketolase -2.97095
NCAPH non-SMC condensin I complex, subunit H -2.95414
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.94463
ALDOC aldolase C, fructose-bisphosphate -2.94249
CDT1 chromatin licensing and DNA replication factor 1 -2.93762
CENPA centromere protein A -2.92109
ATRIP ATR interacting protein -2.9145
TMEM109 transmembrane protein 109 -2.9091
CISD1 CDGSH iron sulfur domain 1 -2.90616
PCLAF PCNA clamp associated factor -2.8978
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.88601
OXA1L oxidase (cytochrome c) assembly 1-like -2.85472
CAPN1 calpain 1, (mu/I) large subunit -2.84655
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.81224
KIF18A kinesin family member 18A -2.81183
CASP8AP2 caspase 8 associated protein 2 -2.80261
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.78845
ZNF16 zinc finger protein 16 -2.77834
FOXM1 forkhead box M1 -2.77571
MDH1 malate dehydrogenase 1, NAD (soluble) -2.77223
DCXR dicarbonyl/L-xylulose reductase -2.763
ZWINT ZW10 interacting kinetochore protein -2.75431
BOLA1 bolA family member 1 -2.74988
DNM1 dynamin 1 -2.74005
FANCI Fanconi anemia, complementation group I -2.73947
PPA2 pyrophosphatase (inorganic) 2 -2.73824
MELK maternal embryonic leucine zipper kinase -2.73274
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.72886
NCAPD2 non-SMC condensin I complex, subunit D2 -2.72602
RRM2 ribonucleotide reductase M2 -2.72421
KIF4A kinesin family member 4A -2.70515
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.70309
BIRC5 baculoviral IAP repeat containing 5 -2.69896
PILRB paired immunoglobin-like type 2 receptor beta -2.69687
MCM9 minichromosome maintenance complex component 9 -2.69377
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.67944
CENPC centromere protein C -2.6737
SLC2A4RG SLC2A4 regulator -2.67248
C2CD5 C2 calcium-dependent domain containing 5 -2.66782
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.663
CENPU centromere protein U -2.66271
ZNF250 zinc finger protein 250 -2.64531
SCYL3 SCY1-like 3 (S. cerevisiae) -2.64247
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -2.63394
CIRBP cold inducible RNA binding protein -2.63258
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.63037
FAM193B family with sequence similarity 193, member B -2.62322
RBM23 RNA binding motif protein 23 -2.61198
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.60839
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.60757
TTK TTK protein kinase -2.59767
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.59648
ERCC6L excision repair cross-complementation group 6-like -2.59292
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.59201
NLRP4 NLR family, pyrin domain containing 4 -2.59095
TBC1D10C TBC1 domain family, member 10C -2.59089
LDHD lactate dehydrogenase D -2.58664
RFC3 replication factor C (activator 1) 3, 38kDa -2.5863
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.5843
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.58262
MAT2B methionine adenosyltransferase II, beta -2.58236
BRIX1 BRX1, biogenesis of ribosomes -2.57885
GEMIN4 gem (nuclear organelle) associated protein 4 -2.5647
GUSB glucuronidase, beta -2.5556
NDC80 NDC80 kinetochore complex component -2.55318
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma -2.53829
MPHOSPH9 M-phase phosphoprotein 9 -2.53556
USP19 ubiquitin specific peptidase 19 -2.52611
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.51756
NNT nicotinamide nucleotide transhydrogenase -2.51081
H2AX H2A.X variant histone -2.49309
PIMREG PICALM interacting mitotic regulator -2.4877
MKI67 marker of proliferation Ki-67 -2.48577
HILPDA hypoxia inducible lipid droplet-associated -2.4852
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.48281
MRPL11 mitochondrial ribosomal protein L11 -2.48209
DNA2 DNA replication helicase/nuclease 2 -2.48121
METTL4 methyltransferase like 4 -2.46985
VRK1 vaccinia related kinase 1 -2.46754
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.4608
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.46074
PFKM phosphofructokinase, muscle -2.45898
H2AZ1 H2A.Z variant histone 1 -2.45594
KRT13 keratin 13, type I -2.4543
CENPM centromere protein M -2.44518
DBF4 DBF4 zinc finger -2.4434
DNAAF2 dynein, axonemal, assembly factor 2 -2.43666
TPX2 TPX2, microtubule-associated -2.43457
TK1 thymidine kinase 1, soluble -2.42776
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -2.4259
MEIS1 Meis homeobox 1 -2.42187
FKBP5 FK506 binding protein 5 -2.41849
ZNF692 zinc finger protein 692 -2.4138
RBM47 RNA binding motif protein 47 -2.41357
VAMP7 vesicle-associated membrane protein 7 -2.41247
MCM6 minichromosome maintenance complex component 6 -2.41029
AUH AU RNA binding protein/enoyl-CoA hydratase -2.4091
YEATS4 YEATS domain containing 4 -2.40896
SH3YL1 SH3 and SYLF domain containing 1 -2.38539
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -2.38437
F8A2 coagulation factor VIII-associated 2 -2.37681
GCLC glutamate-cysteine ligase, catalytic subunit -2.37317
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.37221
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.36966
KIF14 kinesin family member 14 -2.36618
NR2F1 nuclear receptor subfamily 2, group F, member 1 -2.3652
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.36501
SPC25 SPC25, NDC80 kinetochore complex component -2.36233
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.35343
MEPCE methylphosphate capping enzyme -2.3225
KDM3B lysine (K)-specific demethylase 3B -2.31978
CBX3 chromobox homolog 3 -2.31671
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.3139
CETN2 centrin, EF-hand protein, 2 -2.31222
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.3113
SETMAR SET domain and mariner transposase fusion gene -2.30946
TTC33 tetratricopeptide repeat domain 33 -2.30804
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -2.3053
RLN2 relaxin 2 -2.30423
GCDH glutaryl-CoA dehydrogenase -2.30388
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 -2.29896
MACROD1 MACRO domain containing 1 -2.29707
PUS1 pseudouridylate synthase 1 -2.29557
UGP2 UDP-glucose pyrophosphorylase 2 -2.28959
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.28646
LOC128966622 putative protein N-methyltransferase FAM86B2 -2.27904
STOML2 stomatin (EPB72)-like 2 -2.27642
ACOD1 aconitate decarboxylase 1 -2.2736
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.27275
ANKRD49 ankyrin repeat domain 49 -2.27228
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.27083
VBP1 von Hippel-Lindau binding protein 1 -2.27007
NKRF NFKB repressing factor -2.26909
GEMIN2 gem (nuclear organelle) associated protein 2 -2.26859
CKS1B CDC28 protein kinase regulatory subunit 1B -2.26829
FMO3 flavin containing monooxygenase 3 -2.25607
PEX11B peroxisomal biogenesis factor 11 beta -2.25152
LIPT1 lipoyltransferase 1 -2.25093
PNPO pyridoxamine 5'-phosphate oxidase -2.25062
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.2496
HAUS4 HAUS augmin-like complex, subunit 4 -2.23625
GLUL glutamate-ammonia ligase -2.23517
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.22677
PFAS phosphoribosylformylglycinamidine synthase -2.22629
MCM5 minichromosome maintenance complex component 5 -2.22374
DSN1 DSN1, MIS12 kinetochore complex component -2.22296
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.22176
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.22141
BTBD2 BTB (POZ) domain containing 2 -2.22022
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.21892
LBR lamin B receptor -2.21794
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -2.21743
TKFC triokinase/FMN cyclase -2.21668
ZDHHC6 zinc finger, DHHC-type containing 6 -2.21532
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -2.21522
MCM10 minichromosome maintenance complex component 10 -2.21128
VAV3 vav 3 guanine nucleotide exchange factor -2.20656
GTF2A2 general transcription factor IIA, 2, 12kDa -2.20255
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -2.20241
E2F8 E2F transcription factor 8 -2.19857
POLM polymerase (DNA directed), mu -2.19854
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.19722
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -2.1937
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.1853
ANO3 anoctamin 3 -2.18464
CDC25C cell division cycle 25C -2.18431
MORC3 MORC family CW-type zinc finger 3 -2.18352
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -2.18336
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -2.18187
SNRPE small nuclear ribonucleoprotein polypeptide E -2.1788
MSMO1 methylsterol monooxygenase 1 -2.17209
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa -2.17124
SCGB1D1 secretoglobin, family 1D, member 1 -2.16748
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.1616
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.15912
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -2.15897
PGAM4 phosphoglycerate mutase family member 4 -2.15866
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.15855
FZD4 frizzled class receptor 4 -2.15804
SCAP SREBF chaperone -2.15305
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.15259
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.15118
FAIM Fas apoptotic inhibitory molecule -2.14991
CRTAP cartilage associated protein -2.14822
ACSL1 acyl-CoA synthetase long-chain family member 1 -2.13621
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.13281
NFIL3 nuclear factor, interleukin 3 regulated -2.12536
TTC31 tetratricopeptide repeat domain 31 -2.12488
COQ9 coenzyme Q9 -2.12473
REV1 REV1, polymerase (DNA directed) -2.12402
ZMYM1 zinc finger, MYM-type 1 -2.12034
ABHD11 abhydrolase domain containing 11 -2.1197
L2HGDH L-2-hydroxyglutarate dehydrogenase -2.11704
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.11046
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.10443
RNF44 ring finger protein 44 -2.10443
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.10353
THYN1 thymocyte nuclear protein 1 -2.1024
DPYD dihydropyrimidine dehydrogenase -2.10152
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -2.10112
CDCA3 cell division cycle associated 3 -2.09766
TFEC transcription factor EC -2.09757
GIMAP4 GTPase, IMAP family member 4 -2.0971
GCA grancalcin, EF-hand calcium binding protein -2.09694
MUC16 mucin 16, cell surface associated -2.09601
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -2.09322
CYCS cytochrome c, somatic -2.09171
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.09159
FEN1 flap structure-specific endonuclease 1 -2.08658
ACAD8 acyl-CoA dehydrogenase family, member 8 -2.08573
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -2.08449
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.08284
KIF23 kinesin family member 23 -2.08275
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.08044
PGAP2 post-GPI attachment to proteins 2 -2.07958
PRELID3B PRELI domain containing 3B -2.07944
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.07853
APMAP adipocyte plasma membrane associated protein -2.07656
HPD 4-hydroxyphenylpyruvate dioxygenase -2.07455
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -2.07319
COQ3 coenzyme Q3 methyltransferase -2.07307
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -2.07119
CRIPT cysteine-rich PDZ-binding protein -2.06755
FBXO34 F-box protein 34 -2.06403
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.06329
ZSCAN16 zinc finger and SCAN domain containing 16 -2.0609
NUP42 nucleoporin 42 -2.05688
F8 coagulation factor VIII, procoagulant component -2.05566
BPHL biphenyl hydrolase-like (serine hydrolase) -2.05555
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -2.05387
KRT4 keratin 4, type II -2.05172
TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase -2.0489
PTTG1 pituitary tumor-transforming 1 -2.04854
NEK2 NIMA-related kinase 2 -2.0478
HMGN4 high mobility group nucleosomal binding domain 4 -2.04685
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.04586
CENPF centromere protein F, 350/400kDa -2.04446
BLM Bloom syndrome, RecQ helicase-like -2.04398
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -2.0435
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -2.04168
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.04151
RAB33B RAB33B, member RAS oncogene family -2.04071
HPCA hippocalcin -2.0396
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 -2.03521
ACIN1 apoptotic chromatin condensation inducer 1 -2.03304
WDR83OS WD repeat domain 83 opposite strand -2.03259
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.02774
FOCAD focadhesin -2.02766
GLRX5 glutaredoxin 5 -2.02493
USP39 ubiquitin specific peptidase 39 -2.02465
C1GALT1C1 C1GALT1-specific chaperone 1 -2.02378
TACC3 transforming, acidic coiled-coil containing protein 3 -2.02009
ATAD2 ATPase family, AAA domain containing 2 -2.01866
MPV17 MpV17 mitochondrial inner membrane protein -2.01722
CAAP1 caspase activity and apoptosis inhibitor 1 -2.01714
TCEAL1 transcription elongation factor A (SII)-like 1 -2.01075
ARHGAP11A Rho GTPase activating protein 11A -2.00185
PAX9 paired box 9 -2.00184
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -2.00182
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.00161
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.00081
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.00052