CRCGN015_MCF10A.WT.HP_24H:H23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description CH-223191 33.62 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 3.94194
ABHD4 abhydrolase domain containing 4 3.90933
AURKB aurora kinase B 3.4902
STAP2 signal transducing adaptor family member 2 3.23479
ABHD6 abhydrolase domain containing 6 2.6957
STIMATE STIM activating enhancer 2.6769
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.4621
MYLK myosin light chain kinase 2.36978
BLMH bleomycin hydrolase 2.33433
TSPOAP1 TSPO associated protein 1 2.17992
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.1767
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.11553
FKBP8 FK506 binding protein 8, 38kDa 2.05951
CNPY3 canopy FGF signaling regulator 3 2.02155
MCUR1 mitochondrial calcium uniporter regulator 1 2.02113

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -4.85452
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.71962
HMG20B high mobility group 20B -4.59348
ARID4B AT rich interactive domain 4B (RBP1-like) -3.48195
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -3.31116
ALDOC aldolase C, fructose-bisphosphate -3.07433
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.75576
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.54628
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.34197
TMEM59 transmembrane protein 59 -2.32677
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -2.29239
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.22591
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.08869
BCAS2 breast carcinoma amplified sequence 2 -2.08673
TSPAN3 tetraspanin 3 -2.04941
SELENOW selenoprotein W -2.03663
CDC25B cell division cycle 25B -2.03446
MTERF3 mitochondrial transcription termination factor 3 -2.02179
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.00399
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -2.00392
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.00239