CRCGN015_MCF10A.WT.HP_24H:H24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description CH-223191 11.21 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

50 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:H24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 5.34003
CIAO3 cytosolic iron-sulfur assembly component 3 3.74247
NISCH nischarin 3.6325
ZFPM1 zinc finger protein, FOG family member 1 2.80324
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.71155
TBX2 T-box 2 2.6813
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 2.65307
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.63663
MPC2 mitochondrial pyruvate carrier 2 2.5513
SSBP2 single-stranded DNA binding protein 2 2.54526
MAGEF1 melanoma antigen family F1 2.54342
RTN2 reticulon 2 2.46571
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.43547
KLHL21 kelch-like family member 21 2.43529
CARMIL1 capping protein regulator and myosin 1 linker 1 2.39111
LRP3 low density lipoprotein receptor-related protein 3 2.32905
CAV3 caveolin 3 2.19907
SHISAL1 shisa like 1 2.19408
RANGAP1 Ran GTPase activating protein 1 2.17411
TOM1L2 target of myb1-like 2 (chicken) 2.16868
RIC8A RIC8 guanine nucleotide exchange factor A 2.16143
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.15776
ARHGAP22 Rho GTPase activating protein 22 2.14411
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.09216
KLHDC3 kelch domain containing 3 2.0648
SRRM5 serine/arginine repetitive matrix 5 2.0641
PISD phosphatidylserine decarboxylase 2.04016
FOS FBJ murine osteosarcoma viral oncogene homolog 2.03877

decreased expression

Symbol Name Standardized Value
CAB39 calcium binding protein 39 -5.73575
KIF14 kinesin family member 14 -4.54852
PCCB propionyl CoA carboxylase, beta polypeptide -3.78078
ATF5 activating transcription factor 5 -3.63103
CREG1 cellular repressor of E1A-stimulated genes 1 -3.37335
ALDOC aldolase C, fructose-bisphosphate -3.24423
NPDC1 neural proliferation, differentiation and control, 1 -2.75706
CDC25B cell division cycle 25B -2.66315
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.62026
KDM3A lysine (K)-specific demethylase 3A -2.6084
CD58 CD58 molecule -2.59997
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.55112
DERA deoxyribose-phosphate aldolase (putative) -2.49003
CHMP4B charged multivesicular body protein 4B -2.41931
TMEM100 transmembrane protein 100 -2.39574
OCEL1 occludin/ELL domain containing 1 -2.34404
HMG20B high mobility group 20B -2.17211
TSPAN3 tetraspanin 3 -2.16321
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.15042
SLC35B1 solute carrier family 35, member B1 -2.12688
TRIP12 thyroid hormone receptor interactor 12 -2.07762
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -2.01185