CRCGN015_MCF10A.WT.HP_24H:I01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 99.96 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

57 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ARID5B AT rich interactive domain 5B (MRF1-like) 5.26476
SSBP2 single-stranded DNA binding protein 2 4.39442
ZW10 zw10 kinetochore protein 4.26015
KDM5D lysine (K)-specific demethylase 5D 3.65679
WFS1 Wolfram syndrome 1 (wolframin) 3.58891
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.32673
ADGRE5 adhesion G protein-coupled receptor E5 3.17664
CNRIP1 cannabinoid receptor interacting protein 1 3.15445
IDE insulin-degrading enzyme 3.1315
LAGE3 L antigen family, member 3 3.12057
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.07673
TBX2 T-box 2 3.06639
SNAP25 synaptosomal-associated protein, 25kDa 3.06425
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.93573
WIF1 WNT inhibitory factor 1 2.92742
PRR7 proline rich 7 (synaptic) 2.87042
AGR2 anterior gradient 2 2.85796
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 2.62941
MAP7 microtubule-associated protein 7 2.49574
AKAP8 A kinase (PRKA) anchor protein 8 2.38839
FCHO1 FCH domain only 1 2.30338
FGFR4 fibroblast growth factor receptor 4 2.28578
SLC10A3 solute carrier family 10, member 3 2.27493
MRGBP MRG/MORF4L binding protein 2.24679
USP9Y ubiquitin specific peptidase 9, Y-linked 2.22572
CCNF cyclin F 2.22289
MIS18A MIS18 kinetochore protein A 2.19805
NSG2 neuronal vesicle trafficking associated 2 2.13536
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.10863
TBPL1 TBP-like 1 2.10111

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -5.56989
MSN moesin -5.03589
NGRN neugrin, neurite outgrowth associated -4.39237
HSPA8 heat shock 70kDa protein 8 -4.19351
CDPF1 cysteine-rich, DPF motif domain containing 1 -3.97209
DSG2 desmoglein 2 -3.94631
CHMP4B charged multivesicular body protein 4B -3.60172
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.46561
C2CD5 C2 calcium-dependent domain containing 5 -3.34458
ALDOC aldolase C, fructose-bisphosphate -3.32178
CREG1 cellular repressor of E1A-stimulated genes 1 -3.22617
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.13025
SMC1A structural maintenance of chromosomes 1A -2.67246
BASP1 brain abundant, membrane attached signal protein 1 -2.58076
CAB39 calcium binding protein 39 -2.45884
COG4 component of oligomeric golgi complex 4 -2.45271
SELE selectin E -2.3995
GPX4 glutathione peroxidase 4 -2.36779
CD81 CD81 molecule -2.22871
ACADVL acyl-CoA dehydrogenase, very long chain -2.14291
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -2.13801
KIFAP3 kinesin-associated protein 3 -2.11791
TKT transketolase -2.1139
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 -2.10148
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.0878
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -2.07712
CD44 CD44 molecule (Indian blood group) -2.03469