CRCGN015_MCF10A.WT.HP_24H:I02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 33.32 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.48673
USP6NL USP6 N-terminal like 5.05634
ADGRE5 adhesion G protein-coupled receptor E5 4.95295
STAP2 signal transducing adaptor family member 2 4.78598
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.33633
MELK maternal embryonic leucine zipper kinase 2.50962
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.23609
PLPP2 phospholipid phosphatase 2 2.224
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.21009
HEATR3 HEAT repeat containing 3 2.20909
TECR trans-2,3-enoyl-CoA reductase 2.13089
NOSIP nitric oxide synthase interacting protein 2.12515
CCL21 chemokine (C-C motif) ligand 21 2.08635
PLXDC2 plexin domain containing 2 2.0242

decreased expression

Symbol Name Standardized Value
TNIP1 TNFAIP3 interacting protein 1 -5.50622
HSPA8 heat shock 70kDa protein 8 -4.92366
C2CD5 C2 calcium-dependent domain containing 5 -4.19288
NPDC1 neural proliferation, differentiation and control, 1 -4.14061
CLSTN2 calsyntenin 2 -2.48791
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.37865
CD83 CD83 molecule -2.24843
ETNK1 ethanolamine kinase 1 -2.21117
OMD osteomodulin -2.16716
SELE selectin E -2.16403
TSG101 tumor susceptibility 101 -2.12628
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 -2.09333
IRF7 interferon regulatory factor 7 -2.08759
FBXO21 F-box protein 21 -2.07616
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.07428
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.06796
AOC1 amine oxidase, copper containing 1 -2.01053
CCL3L3 chemokine (C-C motif) ligand 3-like 3 -2.00138