CRCGN015_MCF10A.WT.HP_24H:I03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

40 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 5.27858
CXCR4 chemokine (C-X-C motif) receptor 4 5.05448
C2CD2 C2 calcium-dependent domain containing 2 4.60898
PNKP polynucleotide kinase 3'-phosphatase 4.36233
KLHL9 kelch-like family member 9 3.96495
GATA2 GATA binding protein 2 3.68583
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.41592
BLTP2 bridge-like lipid transfer protein family member 2 3.06187
KIF5C kinesin family member 5C 2.99938
TPD52L2 tumor protein D52-like 2 2.72995
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.67794
SMIM40 small integral membrane protein 40 2.5544
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.26739
UNC119B unc-119 homolog B (C. elegans) 2.15539
BCL7B B-cell CLL/lymphoma 7B 2.11768
GADD45A growth arrest and DNA-damage-inducible, alpha 2.10991
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 2.06231
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 2.05165
CCNA1 cyclin A1 2.02439
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 2.01819

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.85022
PCNA proliferating cell nuclear antigen -4.41723
DIPK1A divergent protein kinase domain 1A -4.27535
ATG3 autophagy related 3 -3.45391
STAT1 signal transducer and activator of transcription 1, 91kDa -3.21859
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.04861
PANK2 pantothenate kinase 2 -2.81863
PROZ protein Z, vitamin K-dependent plasma glycoprotein -2.48374
SLC35A5 solute carrier family 35, member A5 -2.42928
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.38824
PHKG2 phosphorylase kinase, gamma 2 (testis) -2.3505
LOC102723713 TP53-target gene 3 protein -2.32017
ATRN attractin -2.19914
OVGP1 oviductal glycoprotein 1, 120kDa -2.17309
DDRGK1 DDRGK domain containing 1 -2.15065
SNX5 sorting nexin 5 -2.14387
KIZ kizuna centrosomal protein -2.11175
WNT10B wingless-type MMTV integration site family, member 10B -2.07037
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.0505
SIRPA signal-regulatory protein alpha -2.04172