CRCGN015_MCF10A.WT.HP_24H:I04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description monoethylhexylphthalate 100.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

44 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.6352
PRR7 proline rich 7 (synaptic) 3.50802
KCTD5 potassium channel tetramerization domain containing 5 3.17246
AGR2 anterior gradient 2 2.81719
ARID5B AT rich interactive domain 5B (MRF1-like) 2.78452
CNPY3 canopy FGF signaling regulator 3 2.74283
STIMATE STIM activating enhancer 2.67745
CXCR4 chemokine (C-X-C motif) receptor 4 2.67237
SYNGAP1 synaptic Ras GTPase activating protein 1 2.57865
NOSIP nitric oxide synthase interacting protein 2.54601
NFIL3 nuclear factor, interleukin 3 regulated 2.51639
IGHMBP2 immunoglobulin mu binding protein 2 2.46826
TCF12 transcription factor 12 2.4294
PPA2 pyrophosphatase (inorganic) 2 2.34272
WIF1 WNT inhibitory factor 1 2.29103
GLRX glutaredoxin (thioltransferase) 2.20267
GSTM5 glutathione S-transferase mu 5 2.19158
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 2.07362
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.03805
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.03406

decreased expression

Symbol Name Standardized Value
HOXA5 homeobox A5 -4.73112
KIF20A kinesin family member 20A -3.96342
CHMP4B charged multivesicular body protein 4B -3.25703
KIF14 kinesin family member 14 -3.08571
YME1L1 YME1-like 1 ATPase -3.0337
HSPA8 heat shock 70kDa protein 8 -2.95666
FAIM Fas apoptotic inhibitory molecule -2.84517
COG7 component of oligomeric golgi complex 7 -2.80907
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.71214
FHL2 four and a half LIM domains 2 -2.54006
SLC25A46 solute carrier family 25, member 46 -2.54002
RBBP5 retinoblastoma binding protein 5 -2.47134
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.33568
BPHL biphenyl hydrolase-like (serine hydrolase) -2.32335
HOXA4 homeobox A4 -2.30826
FLCN folliculin -2.21177
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.17767
PMVK phosphomevalonate kinase -2.1603
ZNF430 zinc finger protein 430 -2.10157
KIF11 kinesin family member 11 -2.09518
TKT transketolase -2.04095
CERT1 ceramide transporter 1 -2.03006
NKAIN1 Na+/K+ transporting ATPase interacting 1 -2.00679
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 -2.00243