CRCGN015_MCF10A.WT.HP_24H:I09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenformin 11.16 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.57785
KLHL21 kelch-like family member 21 4.34035
CNPY3 canopy FGF signaling regulator 3 2.98177
CENPE centromere protein E, 312kDa 2.72247
TRAPPC4 trafficking protein particle complex 4 2.24949
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.23296
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 2.2005
CHN1 chimerin 1 2.18373
SYNGR3 synaptogyrin 3 2.04411
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 2.00706

decreased expression

Symbol Name Standardized Value
SCYL3 SCY1-like 3 (S. cerevisiae) -5.92058
NPDC1 neural proliferation, differentiation and control, 1 -5.36027
ISOC1 isochorismatase domain containing 1 -5.04377
RNF167 ring finger protein 167 -4.60765
PUF60 poly-U binding splicing factor 60KDa -3.76164
MSN moesin -3.75855
PFN1 profilin 1 -3.37941
NUSAP1 nucleolar and spindle associated protein 1 -3.27397
RBM34 RNA binding motif protein 34 -3.04154
NT5DC2 5'-nucleotidase domain containing 2 -2.5329
GGPS1 geranylgeranyl diphosphate synthase 1 -2.27202
PON2 paraoxonase 2 -2.21434
IGFLR1 IGF-like family receptor 1 -2.10916
TTYH1 tweety family member 1 -2.10212
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -2.09554
DNAAF11 dynein axonemal assembly factor 11 -2.08323
TBCE tubulin folding cofactor E -2.07789