CRCGN015_MCF10A.WT.HP_24H:I10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aroclor 1260 95.81 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

45 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HOXA5 homeobox A5 7.93237
NRIP1 nuclear receptor interacting protein 1 4.92686
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.92187
AGR2 anterior gradient 2 3.63153
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.52949
PRKCD protein kinase C, delta 3.45436
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 3.05256
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.88838
FPGS folylpolyglutamate synthase 2.75854
MUC4 mucin 4, cell surface associated 2.73923
TIAM1 T-cell lymphoma invasion and metastasis 1 2.72839
CIAO3 cytosolic iron-sulfur assembly component 3 2.66521
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.49317
CHEK1 checkpoint kinase 1 2.49086
TPD52L2 tumor protein D52-like 2 2.42335
HBA1 hemoglobin, alpha 1 2.28958
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.22828
PLS1 plastin 1 2.19689
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.19126
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.16794
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.16244
PRDX4 peroxiredoxin 4 2.13742
TSKU tsukushi, small leucine rich proteoglycan 2.11924
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 2.10903
BACE2 beta-site APP-cleaving enzyme 2 2.06244
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 2.02809
ITK IL2-inducible T-cell kinase 2.02519

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.9015
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.89826
PCNA proliferating cell nuclear antigen -2.94713
GADD45B growth arrest and DNA-damage-inducible, beta -2.68472
AMT aminomethyltransferase -2.53316
SYPL1 synaptophysin-like 1 -2.50257
MACF1 microtubule-actin crosslinking factor 1 -2.31447
EDN1 endothelin 1 -2.29864
TRIB3 tribbles pseudokinase 3 -2.27852
TMEM230 transmembrane protein 230 -2.18609
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -2.17308
MSMO1 methylsterol monooxygenase 1 -2.15643
S100A1 S100 calcium binding protein A1 -2.15231
TP53BP1 tumor protein p53 binding protein 1 -2.08236
CDHR1 cadherin-related family member 1 -2.05265
KRT23 keratin 23, type I -2.04408
BHMT2 betaine--homocysteine S-methyltransferase 2 -2.04196
LOC122539214 Zinc finger protein LOC122539214 -2.02064