CRCGN015_MCF10A.WT.HP_24H:I11 Gene Set
Genes
27 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LAGE3
|
L antigen family, member 3
|
3.8582
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.7423
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.25515
|
|
PDIA5
|
protein disulfide isomerase family A, member 5
|
3.12515
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.11229
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.92742
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.81916
|
|
SDHB
|
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
|
2.54193
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.41582
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
2.06816
|
|
CDK4
|
cyclin-dependent kinase 4
|
2.06191
|
|
WIF1
|
WNT inhibitory factor 1
|
2.02728
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
-7.38437
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-4.73001
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.52696
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-4.05134
|
|
TENT4A
|
terminal nucleotidyltransferase 4A
|
-3.27259
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-3.24472
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.69534
|
|
SQLE
|
squalene epoxidase
|
-2.4149
|
|
S100A8
|
S100 calcium binding protein A8
|
-2.39378
|
|
TKT
|
transketolase
|
-2.35
|
|
LGALSL
|
lectin, galactoside-binding-like
|
-2.30915
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.13076
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-2.12401
|
|
ELOVL4
|
ELOVL fatty acid elongase 4
|
-2.03746
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.00605
|
