CRCGN015_MCF10A.WT.HP_24H:I16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc yellow 4 99.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

47 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 5.29274
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.13948
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.72642
ADAT1 adenosine deaminase, tRNA-specific 1 3.31111
EPHB2 EPH receptor B2 3.19663
PDIA5 protein disulfide isomerase family A, member 5 2.98578
PKN1 protein kinase N1 2.74714
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.66481
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.64703
FKTN fukutin 2.50569
COQ8A coenzyme Q8A 2.44853
NEK4 NIMA-related kinase 4 2.30532
LARS1 leucyl-tRNA synthetase 1 2.22004
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing 2.21953
ZNF189 zinc finger protein 189 2.17221
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.16168
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 2.11227
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.09881
AAMDC adipogenesis associated, Mth938 domain containing 2.08669
CDK20 cyclin-dependent kinase 20 2.06902
FBXO11 F-box protein 11 2.06709
KCTD12 potassium channel tetramerization domain containing 12 2.06653
TLCD3A TLC domain containing 3A 2.05796
STX18 syntaxin 18 2.05789
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.0572
CCNG1 cyclin G1 2.05627
RBP1 retinol binding protein 1, cellular 2.01416
TFCP2 transcription factor CP2 2.01265

decreased expression

Symbol Name Standardized Value
TSPAN4 tetraspanin 4 -5.06086
DERA deoxyribose-phosphate aldolase (putative) -4.48061
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.44271
PGAM4 phosphoglycerate mutase family member 4 -4.35156
ARPP19 cAMP-regulated phosphoprotein, 19kDa -4.33535
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -4.13069
TENT4A terminal nucleotidyltransferase 4A -3.49187
MTERF3 mitochondrial transcription termination factor 3 -2.30601
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.29898
STX4 syntaxin 4 -2.20802
TGFB3 transforming growth factor, beta 3 -2.16625
PTPRM protein tyrosine phosphatase, receptor type, M -2.15842
CSRP1 cysteine and glycine-rich protein 1 -2.13472
NINJ1 ninjurin 1 -2.1288
SFRP5 secreted frizzled-related protein 5 -2.11128
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -2.06647
EMCN endomucin -2.0439
CST2 cystatin SA -2.0141
LUC7L LUC7-like (S. cerevisiae) -2.00227