| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hc yellow 4 33.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 4.1886 |
| AGR2 | anterior gradient 2 | 3.6716 |
| STK10 | serine/threonine kinase 10 | 3.61136 |
| MCOLN1 | mucolipin 1 | 3.41941 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 3.13295 |
| COMP | cartilage oligomeric matrix protein | 3.02412 |
| SESN1 | sestrin 1 | 2.91733 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 2.75123 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.70604 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.56983 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 2.46846 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 2.43343 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.4251 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 2.39508 |
| ZNF276 | zinc finger protein 276 | 2.38235 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 2.34577 |
| COMMD3-BMI1 | COMMD3-BMI1 readthrough | 2.31578 |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 2.28813 |
| LILRB5 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 | 2.21128 |
| EXOSC10 | exosome component 10 | 2.1649 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 2.16346 |
| LOC124905743 | low affinity immunoglobulin gamma Fc region receptor III-B | 2.15919 |
| MRC1 | mannose receptor, C type 1 | 2.13409 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | 2.12734 |
| TSPAN6 | tetraspanin 6 | 2.11127 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 2.09402 |
| PRKCH | protein kinase C, eta | 2.08024 |
| DEXI | Dexi homolog (mouse) | 2.05791 |
| EVI2B | ecotropic viral integration site 2B | 2.0532 |
| PCDHB11 | protocadherin beta 11 | 2.03792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.03311 |
| PRPF4 | pre-mRNA processing factor 4 | -3.77969 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.64089 |
| PUF60 | poly-U binding splicing factor 60KDa | -3.42131 |
| HMG20B | high mobility group 20B | -3.38681 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -3.30589 |
| RGS2 | regulator of G-protein signaling 2 | -3.28668 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -3.07331 |
| TRIB3 | tribbles pseudokinase 3 | -2.91336 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.76939 |
| VDAC1 | voltage-dependent anion channel 1 | -2.55638 |
| SOX12 | SRY (sex determining region Y)-box 12 | -2.40795 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -2.4056 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.39156 |
| FAIM | Fas apoptotic inhibitory molecule | -2.38141 |
| IL21R | interleukin 21 receptor | -2.37414 |
| EOLA1 | endothelium and lymphocyte associated ASCH domain 1 | -2.3588 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.33545 |
| NDRG1 | N-myc downstream regulated 1 | -2.22557 |
| ATP11B | ATPase, class VI, type 11B | -2.21264 |
| GDF15 | growth differentiation factor 15 | -2.20809 |
| BCAS4 | breast carcinoma amplified sequence 4 | -2.19798 |
| PRR15L | proline rich 15-like | -2.19796 |
| BLNK | B-cell linker | -2.19132 |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | -2.17684 |
| ZNF804A | zinc finger protein 804A | -2.14215 |
| MOSPD1 | motile sperm domain containing 1 | -2.12689 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -2.11243 |
| CD81 | CD81 molecule | -2.11037 |
| DSTN | destrin (actin depolymerizing factor) | -2.08725 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) | -2.06974 |
| CBX6 | chromobox homolog 6 | -2.02548 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.02543 |
| CD9 | CD9 molecule | -2.02146 |
| SCPEP1 | serine carboxypeptidase 1 | -2.01969 |
| EFHD1 | EF-hand domain family, member D1 | -2.01262 |
