CRCGN015_MCF10A.WT.HP_24H:I18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc yellow 4 11.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

44 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 5.09341
CXCR4 chemokine (C-X-C motif) receptor 4 4.67701
MEF2C myocyte enhancer factor 2C 4.42406
AGR2 anterior gradient 2 4.02735
CCL2 chemokine (C-C motif) ligand 2 3.44965
RB1 retinoblastoma 1 3.28185
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.1673
MELK maternal embryonic leucine zipper kinase 3.02724
IGHMBP2 immunoglobulin mu binding protein 2 2.99338
PLAC8 placenta-specific 8 2.71941
SATB1 SATB homeobox 1 2.62106
PKN1 protein kinase N1 2.59185
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.59036
CCDC88C coiled-coil domain containing 88C 2.48059
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.39437
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 2.3939
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.37507
SESN1 sestrin 1 2.32285
CNRIP1 cannabinoid receptor interacting protein 1 2.28968
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.28028
COQ6 coenzyme Q6 monooxygenase 2.26467
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 2.25412
GIMAP4 GTPase, IMAP family member 4 2.22319
STX17 syntaxin 17 2.19336
ICAM2 intercellular adhesion molecule 2 2.1689
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.11875
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.11792
ETV6 ets variant 6 2.09935
CASQ2 calsequestrin 2 (cardiac muscle) 2.09856
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.07601
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.06379
SELPLG selectin P ligand 2.06204
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 2.0428
TPM3 tropomyosin 3 2.02899
CD1D CD1d molecule 2.02429

decreased expression

Symbol Name Standardized Value
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -5.47817
HMG20B high mobility group 20B -5.16282
CD81 CD81 molecule -4.61295
BASP1 brain abundant, membrane attached signal protein 1 -3.15903
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -2.43751
TENT4A terminal nucleotidyltransferase 4A -2.12223
CXCR5 chemokine (C-X-C motif) receptor 5 -2.11613
MAEA macrophage erythroblast attacher -2.07208
AKAP17A A kinase (PRKA) anchor protein 17A -2.0654