CRCGN015_MCF10A.WT.HP_24H:I23 Gene Set
Genes
53 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.67307
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.17321
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
4.03832
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
3.30172
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.76596
|
|
DHX16
|
DEAH (Asp-Glu-Ala-His) box polypeptide 16
|
2.42575
|
|
IL1B
|
interleukin 1, beta
|
2.42364
|
|
RNPEP
|
arginyl aminopeptidase (aminopeptidase B)
|
2.28785
|
|
RGS7
|
regulator of G-protein signaling 7
|
2.24767
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
2.24644
|
|
AURKB
|
aurora kinase B
|
2.20007
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.15333
|
|
UGP2
|
UDP-glucose pyrophosphorylase 2
|
2.15274
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.14698
|
|
FBP1
|
fructose-1,6-bisphosphatase 1
|
2.12471
|
|
MILR1
|
mast cell immunoglobulin-like receptor 1
|
2.11577
|
|
ZSCAN9
|
zinc finger and SCAN domain containing 9
|
2.1135
|
|
TGFB3
|
transforming growth factor, beta 3
|
2.11299
|
|
WDR7
|
WD repeat domain 7
|
2.0654
|
|
VPS37C
|
vacuolar protein sorting 37 homolog C (S. cerevisiae)
|
2.05704
|
|
USP2
|
ubiquitin specific peptidase 2
|
2.03525
|
|
COMP
|
cartilage oligomeric matrix protein
|
2.02757
|
|
FPGS
|
folylpolyglutamate synthase
|
2.01277
|
|
FDX1
|
ferredoxin 1
|
2.01043
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GDF15
|
growth differentiation factor 15
|
-9.5268
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.80318
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.61741
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-4.43887
|
|
GOLT1B
|
golgi transport 1B
|
-4.38926
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-4.09911
|
|
MSN
|
moesin
|
-3.34919
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.15558
|
|
CD320
|
CD320 molecule
|
-2.84694
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.81841
|
|
RPA3
|
replication protein A3, 14kDa
|
-2.81351
|
|
SQSTM1
|
sequestosome 1
|
-2.78465
|
|
ETV6
|
ets variant 6
|
-2.74235
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.65843
|
|
TP53
|
tumor protein p53
|
-2.61697
|
|
NUP88
|
nucleoporin 88kDa
|
-2.56194
|
|
THAP11
|
THAP domain containing 11
|
-2.52463
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.50778
|
|
LOC107986346
|
mitochondrial import receptor subunit TOM7 homolog
|
-2.50096
|
|
MCM3
|
minichromosome maintenance complex component 3
|
-2.43462
|
|
COG4
|
component of oligomeric golgi complex 4
|
-2.41266
|
|
SARAF
|
store-operated calcium entry-associated regulatory factor
|
-2.39591
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-2.34226
|
|
SMIM10L1
|
small integral membrane protein 10 like 1
|
-2.22404
|
|
ERGIC2
|
ERGIC and golgi 2
|
-2.21919
|
|
WBP11
|
WW domain binding protein 11
|
-2.21221
|
|
RPL36
|
ribosomal protein L36
|
-2.19677
|
|
E2F2
|
E2F transcription factor 2
|
-2.16829
|
|
RECQL
|
RecQ helicase-like
|
-2.13254
|