| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hydrazobenzene 101.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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60 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 7.08996 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 3.97872 |
| TRIM13 | tripartite motif containing 13 | 3.73477 |
| MSRA | methionine sulfoxide reductase A | 3.69044 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.12375 |
| EPN2 | epsin 2 | 3.06032 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.05738 |
| CHAMP1 | chromosome alignment maintaining phosphoprotein 1 | 2.8369 |
| RSBN1 | round spermatid basic protein 1 | 2.77787 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.6585 |
| ZNF589 | zinc finger protein 589 | 2.58259 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.47226 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.34996 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 2.34458 |
| DIXDC1 | DIX domain containing 1 | 2.33936 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.32978 |
| FZD7 | frizzled class receptor 7 | 2.30444 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide | 2.27339 |
| TMEM177 | transmembrane protein 177 | 2.26912 |
| AUNIP | aurora kinase A and ninein interacting protein | 2.17782 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 | 2.10176 |
| MTX2 | metaxin 2 | 2.0969 |
| HBE1 | hemoglobin, epsilon 1 | 2.07586 |
| MEIS2 | Meis homeobox 2 | 2.07095 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 2.04158 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 2.02364 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 2.02263 |
| ZBTB48 | zinc finger and BTB domain containing 48 | 2.01774 |
| CCNE1 | cyclin E1 | 2.0069 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.36812 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -5.21069 |
| GOLT1B | golgi transport 1B | -5.15807 |
| CDK4 | cyclin-dependent kinase 4 | -4.0596 |
| THAP11 | THAP domain containing 11 | -3.06957 |
| RBM34 | RNA binding motif protein 34 | -3.01563 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.84705 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -2.73534 |
| HLA-C | major histocompatibility complex, class I, C | -2.44974 |
| KRT1 | keratin 1, type II | -2.34638 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -2.29353 |
| BACE1 | beta-site APP-cleaving enzyme 1 | -2.28417 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -2.24494 |
| UBE2A | ubiquitin-conjugating enzyme E2A | -2.24081 |
| CLTB | clathrin, light chain B | -2.23283 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -2.2323 |
| OSTF1 | osteoclast stimulating factor 1 | -2.20367 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.18028 |
| ATG3 | autophagy related 3 | -2.17947 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) | -2.17662 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.17635 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.17259 |
| NELFE | negative elongation factor complex member E | -2.15445 |
| TBCE | tubulin folding cofactor E | -2.15024 |
| RNF113A | ring finger protein 113A | -2.12614 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -2.11943 |
| FOXA2 | forkhead box A2 | -2.06337 |
| ALDOC | aldolase C, fructose-bisphosphate | -2.03335 |
| MACROH2A2 | macroH2A.2 histone | -2.01863 |
| SRFBP1 | serum response factor binding protein 1 | -2.01565 |
| HLA-B | major histocompatibility complex, class I, B | -2.00702 |