CRCGN015_MCF10A.WT.HP_24H:J01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hydrazobenzene 101.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

60 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 7.08996
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.97872
TRIM13 tripartite motif containing 13 3.73477
MSRA methionine sulfoxide reductase A 3.69044
LYN LYN proto-oncogene, Src family tyrosine kinase 3.12375
EPN2 epsin 2 3.06032
ACAA1 acetyl-CoA acyltransferase 1 3.05738
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.8369
RSBN1 round spermatid basic protein 1 2.77787
IGHMBP2 immunoglobulin mu binding protein 2 2.6585
ZNF589 zinc finger protein 589 2.58259
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.47226
PDIA5 protein disulfide isomerase family A, member 5 2.34996
ZCCHC2 zinc finger, CCHC domain containing 2 2.34458
DIXDC1 DIX domain containing 1 2.33936
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.32978
FZD7 frizzled class receptor 7 2.30444
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.27339
TMEM177 transmembrane protein 177 2.26912
AUNIP aurora kinase A and ninein interacting protein 2.17782
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 2.10176
MTX2 metaxin 2 2.0969
HBE1 hemoglobin, epsilon 1 2.07586
MEIS2 Meis homeobox 2 2.07095
ADGRA3 adhesion G protein-coupled receptor A3 2.04158
KCTD3 potassium channel tetramerization domain containing 3 2.02364
DYNLT1 dynein, light chain, Tctex-type 1 2.02263
ZBTB48 zinc finger and BTB domain containing 48 2.01774
CCNE1 cyclin E1 2.0069

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.36812
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -5.21069
GOLT1B golgi transport 1B -5.15807
CDK4 cyclin-dependent kinase 4 -4.0596
THAP11 THAP domain containing 11 -3.06957
RBM34 RNA binding motif protein 34 -3.01563
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.84705
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.73534
HLA-C major histocompatibility complex, class I, C -2.44974
KRT1 keratin 1, type II -2.34638
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -2.29353
BACE1 beta-site APP-cleaving enzyme 1 -2.28417
GGPS1 geranylgeranyl diphosphate synthase 1 -2.24494
UBE2A ubiquitin-conjugating enzyme E2A -2.24081
CLTB clathrin, light chain B -2.23283
SCYL3 SCY1-like 3 (S. cerevisiae) -2.2323
OSTF1 osteoclast stimulating factor 1 -2.20367
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.18028
ATG3 autophagy related 3 -2.17947
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -2.17662
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.17635
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.17259
NELFE negative elongation factor complex member E -2.15445
TBCE tubulin folding cofactor E -2.15024
RNF113A ring finger protein 113A -2.12614
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -2.11943
FOXA2 forkhead box A2 -2.06337
ALDOC aldolase C, fructose-bisphosphate -2.03335
MACROH2A2 macroH2A.2 histone -2.01863
SRFBP1 serum response factor binding protein 1 -2.01565
HLA-B major histocompatibility complex, class I, B -2.00702