CRCGN015_MCF10A.WT.HP_24H:J02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hydrazobenzene 33.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IDE insulin-degrading enzyme 6.30841
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.47548
IGHMBP2 immunoglobulin mu binding protein 2 3.37705
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.22903
APOE apolipoprotein E 2.88406
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.74991
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.63539
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.25041
LORICRIN loricrin cornified envelope precursor protein 2.14927
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.05236

decreased expression

Symbol Name Standardized Value
TEX10 testis expressed 10 -4.88001
KIF20A kinesin family member 20A -4.2666
CDC20 cell division cycle 20 -3.83012
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.72025
TNIP1 TNFAIP3 interacting protein 1 -2.65112
ZDHHC6 zinc finger, DHHC-type containing 6 -2.50282
SCYL3 SCY1-like 3 (S. cerevisiae) -2.42612
COG2 component of oligomeric golgi complex 2 -2.41196
HSPA1A heat shock 70kDa protein 1A -2.37443
TKT transketolase -2.33154
STAT1 signal transducer and activator of transcription 1, 91kDa -2.16057
KRT19 keratin 19, type I -2.15057
IL1A interleukin 1, alpha -2.09814
MYL1 myosin, light chain 1, alkali; skeletal, fast -2.07068
TNNC2 troponin C type 2 (fast) -2.03333