CRCGN015_MCF10A.WT.HP_24H:J05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl toluene 33.32 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WIF1 WNT inhibitory factor 1 5.67277
GPER1 G protein-coupled estrogen receptor 1 5.13974
SPAG4 sperm associated antigen 4 4.29068
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.79054
PDIA5 protein disulfide isomerase family A, member 5 3.10332
FBXL12 F-box and leucine-rich repeat protein 12 2.92553
IGHMBP2 immunoglobulin mu binding protein 2 2.83115
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.63939
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 2.50755
RPP38 ribonuclease P/MRP 38kDa subunit 2.43328
GPHRA golgi pH regulator A 2.3917
TIMP2 TIMP metallopeptidase inhibitor 2 2.32175
CHAD chondroadherin 2.15893
HLA-DRA major histocompatibility complex, class II, DR alpha 2.06475

decreased expression

Symbol Name Standardized Value
CHIC2 cysteine-rich hydrophobic domain 2 -4.67083
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.50136
SLC35F2 solute carrier family 35, member F2 -4.26942
VDAC1 voltage-dependent anion channel 1 -4.01773
MSN moesin -3.99398
HAT1 histone acetyltransferase 1 -3.93315
SCYL3 SCY1-like 3 (S. cerevisiae) -3.84972
DYNLT3 dynein, light chain, Tctex-type 3 -3.63867
PFN1 profilin 1 -3.49836
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.01993
OLA1 Obg-like ATPase 1 -2.62056
ATG3 autophagy related 3 -2.62001
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.55248
GGCT gamma-glutamylcyclotransferase -2.18326
SEC61G Sec61 gamma subunit -2.12292
GMFG glia maturation factor, gamma -2.10226
S100A11 S100 calcium binding protein A11 -2.02174
MGST3 microsomal glutathione S-transferase 3 -2.01333