CRCGN015_MCF10A.WT.HP_24H:J09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethinyl estradiol 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 4.22442
CNPY3 canopy FGF signaling regulator 3 4.0866
ACLY ATP citrate lyase 3.71804
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3.53925
KIF5C kinesin family member 5C 3.4344
ACAA1 acetyl-CoA acyltransferase 1 3.25789
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.253
ADRB2 adrenoceptor beta 2, surface 3.05976
RAB23 RAB23, member RAS oncogene family 2.49166
MCUR1 mitochondrial calcium uniporter regulator 1 2.47032
PLSCR3 phospholipid scramblase 3 2.45757
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.30038
GIN1 gypsy retrotransposon integrase 1 2.1677
CHN1 chimerin 1 2.15946
CXCL2 chemokine (C-X-C motif) ligand 2 2.15451
NUCB2 nucleobindin 2 2.14733
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.13641

decreased expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 -4.15654
CREG1 cellular repressor of E1A-stimulated genes 1 -3.15783
CANT1 calcium activated nucleotidase 1 -3.06594
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.80903
KATNIP katanin interacting protein -2.74069
RBM15B RNA binding motif protein 15B -2.62724
PARM1 prostate androgen-regulated mucin-like protein 1 -2.4296
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.34753
TENT4A terminal nucleotidyltransferase 4A -2.29948
ASIC2 acid sensing (proton gated) ion channel 2 -2.2151
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.19072
NT5DC2 5'-nucleotidase domain containing 2 -2.11071
POU2F1 POU class 2 homeobox 1 -2.11024
RERGL RERG/RAS-like -2.09647
SCNN1B sodium channel, non voltage gated 1 beta subunit -2.0721
FNDC11 fibronectin type III domain containing 11 -2.06211
IL10RB interleukin 10 receptor, beta -2.02877
STXBP2 syntaxin binding protein 2 -2.02085
GRK3 G protein-coupled receptor kinase 3 -2.01447
UBFD1 ubiquitin family domain containing 1 -2.01003