CRCGN015_MCF10A.WT.HP_24H:J13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosodiethylamine 100.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 3.30569
BAMBI BMP and activin membrane-bound inhibitor 3.23621
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.20805
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.88139
WIF1 WNT inhibitory factor 1 2.64167
MSRA methionine sulfoxide reductase A 2.47892
MAST2 microtubule associated serine/threonine kinase 2 2.31123
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 2.25783
ZBTB16 zinc finger and BTB domain containing 16 2.10389
EVL Enah/Vasp-like 2.04824
NR1D2 nuclear receptor subfamily 1, group D, member 2 2.03083
MELK maternal embryonic leucine zipper kinase 2.01061

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -6.87989
BASP1 brain abundant, membrane attached signal protein 1 -3.92861
MAPK13 mitogen-activated protein kinase 13 -3.89373
DIPK1A divergent protein kinase domain 1A -3.85676
TIMP1 TIMP metallopeptidase inhibitor 1 -3.48764
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.2744
PCCB propionyl CoA carboxylase, beta polypeptide -3.16628
HMG20B high mobility group 20B -2.96999
PMM2 phosphomannomutase 2 -2.78918
CHMP4B charged multivesicular body protein 4B -2.76806
TRAPPC3 trafficking protein particle complex 3 -2.73811
VDAC1 voltage-dependent anion channel 1 -2.67398
KIF14 kinesin family member 14 -2.51111
MTERF3 mitochondrial transcription termination factor 3 -2.34819
ATG3 autophagy related 3 -2.25814
ANXA2 annexin A2 -2.25498
PANX1 pannexin 1 -2.2347
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.18925
HEATR1 HEAT repeat containing 1 -2.12384