CRCGN015_MCF10A.WT.HP_24H:J14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosodiethylamine 33.43 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CARMIL1 capping protein regulator and myosin 1 linker 1 4.2934
SPAG4 sperm associated antigen 4 4.02752
E2F2 E2F transcription factor 2 3.69828
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.47345
STIMATE STIM activating enhancer 3.23965
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.87521
FGFR4 fibroblast growth factor receptor 4 2.83124
SIRT3 sirtuin 3 2.60861
CCL2 chemokine (C-C motif) ligand 2 2.44142
MELK maternal embryonic leucine zipper kinase 2.18803
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 2.07071

decreased expression

Symbol Name Standardized Value
SCYL3 SCY1-like 3 (S. cerevisiae) -3.44795
TXNDC9 thioredoxin domain containing 9 -3.28954
HOXA5 homeobox A5 -2.93409
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.9099
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.55804
FBXO21 F-box protein 21 -2.1664
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.11752