CRCGN015_MCF10A.WT.HP_24H:J15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosodiethylamine 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HYOU1 hypoxia up-regulated 1 3.30773
EPHB2 EPH receptor B2 3.15834
HBA1 hemoglobin, alpha 1 3.0831
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.63908
PDIA5 protein disulfide isomerase family A, member 5 2.49445
ACAA1 acetyl-CoA acyltransferase 1 2.46312
E2F2 E2F transcription factor 2 2.24455
NKAPD1 NKAP domain containing 1 2.06917
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.05726
SESN1 sestrin 1 2.03044
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.02507

decreased expression

Symbol Name Standardized Value
DNM1L dynamin 1-like -3.80608
CD320 CD320 molecule -3.75414
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -3.63516
CYCS cytochrome c, somatic -3.5247
RPIA ribose 5-phosphate isomerase A -3.48911
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.30416
TUBB6 tubulin, beta 6 class V -3.28891
JMJD6 jumonji domain containing 6 -2.785
TENT4A terminal nucleotidyltransferase 4A -2.73353
RGS2 regulator of G-protein signaling 2 -2.47976
UFM1 ubiquitin-fold modifier 1 -2.46273
LDHB lactate dehydrogenase B -2.45931
CTNND1 catenin (cadherin-associated protein), delta 1 -2.3332
PMM2 phosphomannomutase 2 -2.29884
TIMP1 TIMP metallopeptidase inhibitor 1 -2.2969
ETNK1 ethanolamine kinase 1 -2.26123
NVL nuclear VCP-like -2.22
MED21 mediator complex subunit 21 -2.21252
SINHCAF SIN3-HDAC complex associated factor -2.15348
RHBDF2 rhomboid 5 homolog 2 (Drosophila) -2.11046
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -2.06048
BTG3 BTG family, member 3 -2.05809
FRZB frizzled-related protein -2.03401
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.02955
KRT14 keratin 14, type I -2.00974