CRCGN015_MCF10A.WT.HP_24H:J17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-(1-naphthyl)ethylenediamine.2hcl 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACLY ATP citrate lyase 2.94803
MAST2 microtubule associated serine/threonine kinase 2 2.90554
S100A4 S100 calcium binding protein A4 2.89883
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.59854
CHEK1 checkpoint kinase 1 2.5036
CERK ceramide kinase 2.03771
IFT46 intraflagellar transport 46 2.00693

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -5.26891
CCNB1 cyclin B1 -4.07378
PCNA proliferating cell nuclear antigen -3.76411
CTNND1 catenin (cadherin-associated protein), delta 1 -3.16263
CD320 CD320 molecule -2.44262
NT5DC2 5'-nucleotidase domain containing 2 -2.2088
MFSD12 major facilitator superfamily domain containing 12 -2.00011