CRCGN015_MCF10A.WT.HP_24H:J21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description simazine 11.34 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
C2CD2 C2 calcium-dependent domain containing 2 4.91406
STAP2 signal transducing adaptor family member 2 4.4618
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.99425
ARID5B AT rich interactive domain 5B (MRF1-like) 3.70982
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.63511
RPL39L ribosomal protein L39-like 3.54376
MAMLD1 mastermind-like domain containing 1 2.53947
MSRA methionine sulfoxide reductase A 2.30246
CASP5 caspase 5, apoptosis-related cysteine peptidase 2.12798
RAB3B RAB3B, member RAS oncogene family 2.11785
ZNF248 zinc finger protein 248 2.08794
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.07781
CDH8 cadherin 8, type 2 2.05321
EPHX2 epoxide hydrolase 2, cytoplasmic 2.04743
APOL3 apolipoprotein L, 3 2.01172

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -4.99198
TUBB6 tubulin, beta 6 class V -4.85524
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.78167
PPIC peptidylprolyl isomerase C (cyclophilin C) -4.67678
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.18768
BASP1 brain abundant, membrane attached signal protein 1 -3.73605
SCYL3 SCY1-like 3 (S. cerevisiae) -2.67599
MPC2 mitochondrial pyruvate carrier 2 -2.62576
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.45611
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -2.10064
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -2.08622
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.04549