CRCGN015_MCF10A.WT.HP_24H:J23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',5,5'-tetrachlorobenzidine 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

941 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:J23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL2 chemokine (C-X-C motif) ligand 2 8.7508
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 8.18695
TNIP1 TNFAIP3 interacting protein 1 6.96518
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.57817
IL1B interleukin 1, beta 5.17804
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 4.65034
STX4 syntaxin 4 4.63253
VGLL4 vestigial-like family member 4 4.60761
C2CD2 C2 calcium-dependent domain containing 2 4.47677
STK10 serine/threonine kinase 10 4.25765
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 4.22771
WIF1 WNT inhibitory factor 1 4.07863
SQSTM1 sequestosome 1 4.02515
MYH9 myosin, heavy chain 9, non-muscle 4.00621
STIMATE STIM activating enhancer 3.97571
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.89102
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 3.80391
STXBP1 syntaxin binding protein 1 3.78845
CXCL3 chemokine (C-X-C motif) ligand 3 3.74031
IER3 immediate early response 3 3.69599
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.64141
CCL20 chemokine (C-C motif) ligand 20 3.60178
NSDHL NAD(P) dependent steroid dehydrogenase-like 3.58558
LSR lipolysis stimulated lipoprotein receptor 3.55827
DCTN1 dynactin 1 3.55535
TRIB3 tribbles pseudokinase 3 3.54095
ALAS1 5'-aminolevulinate synthase 1 3.53068
BMP4 bone morphogenetic protein 4 3.52766
STAP2 signal transducing adaptor family member 2 3.43068
VAT1 vesicle amine transport 1 3.41507
TICAM1 toll-like receptor adaptor molecule 1 3.41069
PMM2 phosphomannomutase 2 3.40877
PYCR1 pyrroline-5-carboxylate reductase 1 3.3855
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.3796
AARS1 alanyl-tRNA synthetase 1 3.34591
AKT1 v-akt murine thymoma viral oncogene homolog 1 3.33939
FAT1 FAT atypical cadherin 1 3.33508
TMEM40 transmembrane protein 40 3.27356
HMOX1 heme oxygenase 1 3.25222
LRP10 low density lipoprotein receptor-related protein 10 3.23383
SMIM40 small integral membrane protein 40 3.20396
SQOR sulfide quinone oxidoreductase 3.19967
GPC1 glypican 1 3.16289
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 3.15709
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 3.13605
NCK2 NCK adaptor protein 2 3.11423
SPATA2L spermatogenesis associated 2-like 3.10703
GARS1 glycyl-tRNA synthetase 1 3.10164
OXSR1 oxidative stress responsive 1 3.09899
TNIP2 TNFAIP3 interacting protein 2 3.09375
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.08773
SIL1 SIL1 nucleotide exchange factor 3.08609
CGB8 chorionic gonadotropin, beta polypeptide 8 3.08488
IFT54 intraflagellar transport 54 3.04697
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 3.01371
CCND3 cyclin D3 3.00617
IL1A interleukin 1, alpha 2.99755
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.99087
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.98932
IRF6 interferon regulatory factor 6 2.98388
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.98384
DUSP4 dual specificity phosphatase 4 2.96149
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 2.95634
ZNF764 zinc finger protein 764 2.95331
H2BC9 H2B clustered histone 9 2.94318
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.93674
ADRM1 adhesion regulating molecule 1 2.93102
CYTH2 cytohesin 2 2.92707
PNPLA6 patatin-like phospholipase domain containing 6 2.92448
TPST2 tyrosylprotein sulfotransferase 2 2.92256
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 2.90126
FYN FYN proto-oncogene, Src family tyrosine kinase 2.89861
GDI1 GDP dissociation inhibitor 1 2.89352
BAD BCL2-associated agonist of cell death 2.88277
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.87526
BRMS1L breast cancer metastasis-suppressor 1-like 2.87419
NTAN1 N-terminal asparagine amidase 2.86941
PWWP3A PWWP domain containing 3A, DNA repair factor 2.8691
AMDHD2 amidohydrolase domain containing 2 2.86724
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.86519
KLC3 kinesin light chain 3 2.85588
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.85054
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 2.83814
MICALL1 MICAL-like 1 2.83778
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.82735
FTSJ3 FtsJ homolog 3 (E. coli) 2.81113
MYBBP1A MYB binding protein (P160) 1a 2.80314
ELAC2 elaC ribonuclease Z 2 2.79379
DOCK4 dedicator of cytokinesis 4 2.78392
ZC3H12A zinc finger CCCH-type containing 12A 2.77464
DAPK3 death-associated protein kinase 3 2.7709
STX2 syntaxin 2 2.76505
TWF2 twinfilin actin binding protein 2 2.759
CAB39 calcium binding protein 39 2.7583
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.75692
MCOLN1 mucolipin 1 2.75198
FSD1 fibronectin type III and SPRY domain containing 1 2.74789
NECAP2 NECAP endocytosis associated 2 2.74575
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.7407
NSD1 nuclear receptor binding SET domain protein 1 2.73588
SH2B3 SH2B adaptor protein 3 2.72875
CBARP CACN subunit beta associated regulatory protein 2.72359
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 2.71263
MYO1D myosin ID 2.71248
PTGDR2 prostaglandin D2 receptor 2 2.70882
IL32 interleukin 32 2.70619
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.70012
RNF126 ring finger protein 126 2.69966
DDRGK1 DDRGK domain containing 1 2.68569
CARS1 cysteinyl-tRNA synthetase 1 2.68246
YEATS2 YEATS domain containing 2 2.65973
COL17A1 collagen, type XVII, alpha 1 2.64097
PYCARD PYD and CARD domain containing 2.62473
KATNIP katanin interacting protein 2.61394
TMEM94 transmembrane protein 94 2.61102
DDA1 DET1 and DDB1 associated 1 2.60973
H2BC12 H2B clustered histone 12 2.60807
TP53BP2 tumor protein p53 binding protein 2 2.59832
CTSL cathepsin L 2.59526
RNF19B ring finger protein 19B 2.59051
GRK3 G protein-coupled receptor kinase 3 2.58423
PLA2G15 phospholipase A2, group XV 2.58067
KRT34 keratin 34, type I 2.57485
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.57418
JAG2 jagged 2 2.56533
VASH1 vasohibin 1 2.5611
MARK4 MAP/microtubule affinity-regulating kinase 4 2.56095
RRAGC Ras-related GTP binding C 2.55875
ZNF768 zinc finger protein 768 2.55174
RUBCN rubicon autophagy regulator 2.55157
TMEM127 transmembrane protein 127 2.54704
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.54502
WASHC5 WASH complex subunit 5 2.52722
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.52615
MBTPS1 membrane-bound transcription factor peptidase, site 1 2.52612
TMEM74B transmembrane protein 74B 2.52234
NCF2 neutrophil cytosolic factor 2 2.52014
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.52012
RAB31 RAB31, member RAS oncogene family 2.51201
ZFAND3 zinc finger, AN1-type domain 3 2.51115
IL15RA interleukin 15 receptor, alpha 2.50559
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 2.49639
FCHO1 FCH domain only 1 2.49456
TSGA10 testis specific, 10 2.48957
H2AC19 H2A clustered histone 19 2.48947
ABR active BCR-related 2.48225
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.48176
DRAM1 DNA-damage regulated autophagy modulator 1 2.48151
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.47767
UGDH UDP-glucose 6-dehydrogenase 2.47053
HYOU1 hypoxia up-regulated 1 2.47022
PICK1 protein interacting with PRKCA 1 2.47009
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 2.46503
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.46314
MYO5A myosin VA (heavy chain 12, myoxin) 2.46278
GALR2 galanin receptor 2 2.4617
CDC34 cell division cycle 34 2.46142
NACAD NAC alpha domain containing 2.45988
MMP15 matrix metallopeptidase 15 (membrane-inserted) 2.45919
AVEN apoptosis, caspase activation inhibitor 2.4547
ADAP2 ArfGAP with dual PH domains 2 2.45402
MTSS1 metastasis suppressor 1 2.45383
RAI14 retinoic acid induced 14 2.45241
CTNS cystinosin, lysosomal cystine transporter 2.44843
NFE2L1 nuclear factor, erythroid 2-like 1 2.44794
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 2.44473
CRLF2 cytokine receptor-like factor 2 2.44061
DPYSL2 dihydropyrimidinase-like 2 2.43943
RBM41 RNA binding motif protein 41 2.4333
PNKP polynucleotide kinase 3'-phosphatase 2.43226
LRRC59 leucine rich repeat containing 59 2.42994
SEC24C SEC24 family member C 2.42718
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.42552
CSRP1 cysteine and glycine-rich protein 1 2.42205
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.42196
PIAS4 protein inhibitor of activated STAT, 4 2.42161
MOK MOK protein kinase 2.41885
CUX2 cut-like homeobox 2 2.41865
FAM114A1 family with sequence similarity 114, member A1 2.41835
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.41084
CYB5R3 cytochrome b5 reductase 3 2.40716
TLK2 tousled-like kinase 2 2.40433
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.40075
PMP22 peripheral myelin protein 22 2.40071
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.39461
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.39379
MVP major vault protein 2.3886
KIAA0930 KIAA0930 2.38782
HDLBP high density lipoprotein binding protein 2.38244
GAS6 growth arrest-specific 6 2.38157
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 2.37919
WWC1 WW and C2 domain containing 1 2.37835
GRB7 growth factor receptor-bound protein 7 2.37624
PRDM4 PR domain containing 4 2.37552
KCTD5 potassium channel tetramerization domain containing 5 2.37482
IL4R interleukin 4 receptor 2.36992
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.36984
LAMB3 laminin, beta 3 2.36948
PALM paralemmin 2.36781
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 2.36538
LAMC2 laminin, gamma 2 2.36467
VWF von Willebrand factor 2.36452
LAMC3 laminin, gamma 3 2.36323
MACO1 macoilin 1 2.3563
WDR13 WD repeat domain 13 2.35621
IBSP integrin-binding sialoprotein 2.35488
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 2.35342
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.35053
FAM50A family with sequence similarity 50, member A 2.34888
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 2.34619
TIMP2 TIMP metallopeptidase inhibitor 2 2.34616
CD163L1 CD163 molecule-like 1 2.34152
NXF3 nuclear RNA export factor 3 2.34127
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 2.33957
MTMR14 myotubularin related protein 14 2.33941
CEP131 centrosomal protein 131kDa 2.33892
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.33516
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.33515
LIG4 ligase IV, DNA, ATP-dependent 2.33084
LONP1 lon peptidase 1, mitochondrial 2.32713
GCC1 GRIP and coiled-coil domain containing 1 2.3236
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 2.3236
AGR2 anterior gradient 2 2.31774
AP3D1 adaptor-related protein complex 3, delta 1 subunit 2.31694
TRIM36 tripartite motif containing 36 2.31671
H2BC5 H2B clustered histone 5 2.31644
LRRC32 leucine rich repeat containing 32 2.31637
E4F1 E4F transcription factor 1 2.31588
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.31552
ZC4H2 zinc finger, C4H2 domain containing 2.31526
EHD1 EH-domain containing 1 2.31226
DENND2A DENN/MADD domain containing 2A 2.31137
MYL9 myosin, light chain 9, regulatory 2.31128
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.311
S1PR5 sphingosine-1-phosphate receptor 5 2.30913
ULBP1 UL16 binding protein 1 2.30675
SART1 squamous cell carcinoma antigen recognized by T cells 2.3066
YIPF3 Yip1 domain family, member 3 2.30658
MON1B MON1 secretory trafficking family member B 2.30318
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.30029
WBP1L WW domain binding protein 1-like 2.29981
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.29865
ICAM1 intercellular adhesion molecule 1 2.2957
PCYT1B phosphate cytidylyltransferase 1, choline, beta 2.29568
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.29455
RAP1GAP RAP1 GTPase activating protein 2.29061
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 2.28884
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.28879
SHISAL1 shisa like 1 2.28782
CELA2B chymotrypsin-like elastase family, member 2B 2.28583
H2BC4 H2B clustered histone 4 2.28545
TMEM132A transmembrane protein 132A 2.28465
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.28368
KRT3 keratin 3, type II 2.28346
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 2.28305
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.28249
CCDC69 coiled-coil domain containing 69 2.26926
EHD4 EH-domain containing 4 2.26864
CDPF1 cysteine-rich, DPF motif domain containing 1 2.2661
UBQLN3 ubiquilin 3 2.26491
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.26188
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.25737
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.25611
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.25204
LRRK1 leucine-rich repeat kinase 1 2.24662
ATRNL1 attractin-like 1 2.24628
USB1 U6 snRNA biogenesis 1 2.24247
KAT2B K(lysine) acetyltransferase 2B 2.24161
SLC38A12 solute carrier family 38 member 12 2.2395
AQP8 aquaporin 8 2.23949
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 2.23769
CSPP1 centrosome and spindle pole associated protein 1 2.23111
CLEC5A C-type lectin domain family 5, member A 2.23033
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.2243
RETN resistin 2.2233
MMP9 matrix metallopeptidase 9 2.22329
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 2.21845
CLIP2 CAP-GLY domain containing linker protein 2 2.21737
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.21266
THAP4 THAP domain containing 4 2.21157
STYK1 serine/threonine/tyrosine kinase 1 2.20933
COL9A2 collagen, type IX, alpha 2 2.20676
TES testin LIM domain protein 2.20557
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.19954
CLTCL1 clathrin, heavy chain-like 1 2.19881
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.19871
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.19737
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.19697
TOR1B torsin family 1, member B (torsin B) 2.19438
ELMO1 engulfment and cell motility 1 2.19327
BMP8B bone morphogenetic protein 8b 2.18515
SPAG1 sperm associated antigen 1 2.1812
RIPK2 receptor-interacting serine-threonine kinase 2 2.18039
LIN37 lin-37 DREAM MuvB core complex component 2.1803
KCTD17 potassium channel tetramerization domain containing 17 2.17864
GPR137B G protein-coupled receptor 137B 2.17842
GRN granulin 2.17841
SEPTIN5 septin 5 2.17726
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.17709
TLCD3A TLC domain containing 3A 2.17694
RAG2 recombination activating gene 2 2.17693
ZC2HC1C zinc finger, C2HC-type containing 1C 2.17638
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.1755
CCP110 centriolar coiled coil protein 110kDa 2.17527
NUDC nudC nuclear distribution protein 2.17073
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.16936
DIPK1A divergent protein kinase domain 1A 2.16713
SCUBE2 signal peptide, CUB domain, EGF-like 2 2.16592
RUNX3 runt-related transcription factor 3 2.16531
CDK14 cyclin-dependent kinase 14 2.16433
ZNF696 zinc finger protein 696 2.16376
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.16229
OSBPL2 oxysterol binding protein-like 2 2.15896
CPTP ceramide-1-phosphate transfer protein 2.15891
PSEN2 presenilin 2 2.1569
GALNS galactosamine (N-acetyl)-6-sulfatase 2.15631
PLXND1 plexin D1 2.15258
NUPR1 nuclear protein, transcriptional regulator, 1 2.14815
BCORL1 BCL6 corepressor-like 1 2.14357
PPP1R26 protein phosphatase 1, regulatory subunit 26 2.14282
JMJD6 jumonji domain containing 6 2.14268
ADAM2 ADAM metallopeptidase domain 2 2.14227
SQLE squalene epoxidase 2.14187
HEATR6 HEAT repeat containing 6 2.14022
BCAP31 B-cell receptor-associated protein 31 2.13715
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.13619
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.13085
VAMP8 vesicle-associated membrane protein 8 2.12587
BTBD7 BTB (POZ) domain containing 7 2.1242
SPI1 Spi-1 proto-oncogene 2.124
RAB8A RAB8A, member RAS oncogene family 2.1202
CAMTA2 calmodulin binding transcription activator 2 2.11888
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 2.11879
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.11851
PHF13 PHD finger protein 13 2.11703
AKAP4 A kinase (PRKA) anchor protein 4 2.11548
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.11101
CCDC88A coiled-coil domain containing 88A 2.11014
MMP17 matrix metallopeptidase 17 (membrane-inserted) 2.10838
PARP12 poly (ADP-ribose) polymerase family, member 12 2.10664
NOMO3 NODAL modulator 3 2.10552
SIRPA signal-regulatory protein alpha 2.10353
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.10258
CANT1 calcium activated nucleotidase 1 2.1024
PITPNA phosphatidylinositol transfer protein, alpha 2.10137
TGFA transforming growth factor, alpha 2.10122
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.1012
HIP1R huntingtin interacting protein 1 related 2.10102
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.09999
GAS2L1 growth arrest-specific 2 like 1 2.09956
KLHL36 kelch-like family member 36 2.09558
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.0952
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.09373
ZNF668 zinc finger protein 668 2.09343
HTRA1 HtrA serine peptidase 1 2.09227
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.09192
GH2 growth hormone 2 2.09159
C3AR1 complement component 3a receptor 1 2.09144
STXBP2 syntaxin binding protein 2 2.09009
CHD8 chromodomain helicase DNA binding protein 8 2.08963
FSHB follicle stimulating hormone, beta polypeptide 2.08898
UBE3C ubiquitin protein ligase E3C 2.08877
PYGB phosphorylase, glycogen; brain 2.08365
EPS8L1 EPS8-like 1 2.08308
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2.08238
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.08201
CDCP1 CUB domain containing protein 1 2.07728
CDH5 cadherin 5, type 2 (vascular endothelium) 2.07536
FSCN2 fascin actin-bundling protein 2, retinal 2.07509
NXN nucleoredoxin 2.07492
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.0703
MYH11 myosin, heavy chain 11, smooth muscle 2.06925
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 2.06907
GATAD2A GATA zinc finger domain containing 2A 2.06874
DOK7 docking protein 7 2.06697
CES3 carboxylesterase 3 2.06618
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.06566
ZNF205 zinc finger protein 205 2.06498
MALT1 MALT1 paracaspase 2.06334
SOCS2 suppressor of cytokine signaling 2 2.06317
PEX14 peroxisomal biogenesis factor 14 2.06268
TXNRD1 thioredoxin reductase 1 2.06233
ZNHIT1 zinc finger, HIT-type containing 1 2.06055
NCF1 neutrophil cytosolic factor 1 2.0605
MAP3K11 mitogen-activated protein kinase kinase kinase 11 2.06036
ATOSB atos homolog B 2.0589
ISG15 ISG15 ubiquitin-like modifier 2.0579
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.0564
PTHLH parathyroid hormone-like hormone 2.05474
CLTB clathrin, light chain B 2.05443
ICAM2 intercellular adhesion molecule 2 2.05414
ZBTB7A zinc finger and BTB domain containing 7A 2.05413
CEMIP2 cell migration inducing hyaluronidase 2 2.0538
DGKE diacylglycerol kinase, epsilon 64kDa 2.05152
FOXL2 forkhead box L2 2.05094
SH2D2A SH2 domain containing 2A 2.04975
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.04794
SIRT6 sirtuin 6 2.04551
MEST mesoderm specific transcript 2.04536
IL24 interleukin 24 2.04446
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 2.044
CD63 CD63 molecule 2.04315
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.0427
TOP6BL TOP6B like initiator of meiotic double strand breaks 2.04244
DENND1B DENN/MADD domain containing 1B 2.04172
POMT2 protein-O-mannosyltransferase 2 2.04003
IPO13 importin 13 2.03866
JADE3 jade family PHD finger 3 2.03675
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.03643
ZNF821 zinc finger protein 821 2.03493
HBEGF heparin-binding EGF-like growth factor 2.03396
PDE4A phosphodiesterase 4A, cAMP-specific 2.03092
GLRX glutaredoxin (thioltransferase) 2.03063
TBCB tubulin folding cofactor B 2.02902
IL12B interleukin 12B 2.02757
RNF25 ring finger protein 25 2.0247
FAF2 Fas associated factor family member 2 2.01944
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.01839
YARS1 tyrosyl-tRNA synthetase 1 2.01833
UBE2O ubiquitin-conjugating enzyme E2O 2.01737
DNAI4 dynein axonemal intermediate chain 4 2.01677
THSD7A thrombospondin, type I, domain containing 7A 2.01636
KRTAP1-1 keratin associated protein 1-1 2.01598
IQSEC2 IQ motif and Sec7 domain 2 2.01416
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.01345
LOC102724560 cystathionine beta-synthase 2.01302
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.01251
ATP11B ATPase, class VI, type 11B 2.0124
CLXN calaxin 2.01235
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.01177
SLC4A2 solute carrier family 4 (anion exchanger), member 2 2.00968
LMBR1 limb development membrane protein 1 2.0096
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.00949
EFCAB6 EF-hand calcium binding domain 6 2.00898
TPD52-MRPS28 TPD52-MRPS28 readthrough 2.00676
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 2.00573
CHIA chitinase, acidic 2.004
INHBE inhibin, beta E 2.00366
CCDC92 coiled-coil domain containing 92 2.0034
FGFR4 fibroblast growth factor receptor 4 2.00071

decreased expression

Symbol Name Standardized Value
HOXA5 homeobox A5 -10.0
UBE2C ubiquitin-conjugating enzyme E2C -9.39244
TOP2A topoisomerase (DNA) II alpha 170kDa -6.95403
OXA1L oxidase (cytochrome c) assembly 1-like -6.69747
DDIT4 DNA-damage-inducible transcript 4 -6.20792
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -5.98074
HADH hydroxyacyl-CoA dehydrogenase -5.75431
CDK1 cyclin-dependent kinase 1 -5.36876
CRTAP cartilage associated protein -5.20638
NUSAP1 nucleolar and spindle associated protein 1 -5.18739
RPA3 replication protein A3, 14kDa -5.17844
CD44 CD44 molecule (Indian blood group) -5.13801
CDC25B cell division cycle 25B -5.04646
CCNA2 cyclin A2 -4.87271
KHDC4 KH domain containing 4, pre-mRNA splicing factor -4.78114
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -4.77674
DCK deoxycytidine kinase -4.72757
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.72743
ALDOC aldolase C, fructose-bisphosphate -4.70757
GTPBP8 GTP-binding protein 8 (putative) -4.67006
CD58 CD58 molecule -4.65136
PPIC peptidylprolyl isomerase C (cyclophilin C) -4.63062
LDHD lactate dehydrogenase D -4.53381
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -4.41419
SESN1 sestrin 1 -4.37946
TEX10 testis expressed 10 -4.1904
GTF2A2 general transcription factor IIA, 2, 12kDa -4.16132
EAPP E2F-associated phosphoprotein -4.11707
PCNA proliferating cell nuclear antigen -4.1166
PCCB propionyl CoA carboxylase, beta polypeptide -4.08125
STMN1 stathmin 1 -4.00139
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.97716
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.96248
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.94692
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.94271
GADD45B growth arrest and DNA-damage-inducible, beta -3.90431
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.80052
NUP133 nucleoporin 133kDa -3.7695
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.76888
BACE2 beta-site APP-cleaving enzyme 2 -3.76222
MSMO1 methylsterol monooxygenase 1 -3.73626
HOXA10 homeobox A10 -3.70907
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.70718
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.69623
RGS2 regulator of G-protein signaling 2 -3.63076
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -3.61282
COPS4 COP9 signalosome subunit 4 -3.57378
CTR9 CTR9, Paf1/RNA polymerase II complex component -3.57136
COQ6 coenzyme Q6 monooxygenase -3.55283
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.53001
CISD1 CDGSH iron sulfur domain 1 -3.51823
TSPAN6 tetraspanin 6 -3.51606
ZDHHC6 zinc finger, DHHC-type containing 6 -3.50008
LYRM1 LYR motif containing 1 -3.48445
GOLGA7 golgin A7 -3.46628
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.45213
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.42466
SNRPE small nuclear ribonucleoprotein polypeptide E -3.4237
CDK4 cyclin-dependent kinase 4 -3.41077
PGM1 phosphoglucomutase 1 -3.38486
C2CD5 C2 calcium-dependent domain containing 5 -3.3838
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -3.37036
TXNDC9 thioredoxin domain containing 9 -3.35491
ACYP1 acylphosphatase 1, erythrocyte (common) type -3.35066
PTCD3 pentatricopeptide repeat domain 3 -3.28483
RBMX RNA binding motif protein, X-linked -3.2791
MNAT1 MNAT CDK-activating kinase assembly factor 1 -3.27493
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.27217
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -3.26524
MDH1 malate dehydrogenase 1, NAD (soluble) -3.26343
CASC3 cancer susceptibility candidate 3 -3.25955
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -3.25906
ACOT2 acyl-CoA thioesterase 2 -3.239
HOXA4 homeobox A4 -3.22837
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.20851
KDM3A lysine (K)-specific demethylase 3A -3.20375
BZW2 basic leucine zipper and W2 domains 2 -3.19774
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -3.16215
ZNHIT3 zinc finger, HIT-type containing 3 -3.1579
DEK DEK proto-oncogene -3.14814
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -3.14471
NLRP4 NLR family, pyrin domain containing 4 -3.14418
MRPS16 mitochondrial ribosomal protein S16 -3.12635
HAT1 histone acetyltransferase 1 -3.12602
LACTB2 lactamase, beta 2 -3.12476
NR1D2 nuclear receptor subfamily 1, group D, member 2 -3.11721
CPNE3 copine III -3.11604
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.09909
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -3.09652
LBR lamin B receptor -3.09446
NFIL3 nuclear factor, interleukin 3 regulated -3.09195
SKP1 S-phase kinase-associated protein 1 -3.08422
MED28 mediator complex subunit 28 -3.08367
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.08135
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.08111
ECD ecdysoneless homolog (Drosophila) -3.0777
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -3.05915
MRPL3 mitochondrial ribosomal protein L3 -3.04546
PRUNE1 prune exopolyphosphatase 1 -3.03475
NNT nicotinamide nucleotide transhydrogenase -3.02782
EIF4E eukaryotic translation initiation factor 4E -3.02638
C1QBP complement component 1, q subcomponent binding protein -3.02638
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.02508
CRYL1 crystallin, lambda 1 -3.02125
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -3.02098
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.0192
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -3.00404
BMPR1A bone morphogenetic protein receptor, type IA -3.00131
FBXO3 F-box protein 3 -2.97825
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.95724
ICAM3 intercellular adhesion molecule 3 -2.95093
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.94408
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.94239
TOMM70 translocase of outer mitochondrial membrane 70 -2.93166
ACY1 aminoacylase 1 -2.93026
HMGB2 high mobility group box 2 -2.924
TM2D3 TM2 domain containing 3 -2.91022
TSC22D3 TSC22 domain family, member 3 -2.90194
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.90133
ATRAID all-trans retinoic acid-induced differentiation factor -2.87693
ARID4A AT rich interactive domain 4A (RBP1-like) -2.87558
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.86647
TCEAL1 transcription elongation factor A (SII)-like 1 -2.85994
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.85752
SKAP2 src kinase associated phosphoprotein 2 -2.85486
FOXJ3 forkhead box J3 -2.8489
THYN1 thymocyte nuclear protein 1 -2.83831
NUP54 nucleoporin 54kDa -2.83404
BCCIP BRCA2 and CDKN1A interacting protein -2.83178
PSRC1 proline/serine-rich coiled-coil 1 -2.82574
IPO7 importin 7 -2.81642
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.81356
TMEM14B transmembrane protein 14B -2.81201
ADI1 acireductone dioxygenase 1 -2.80887
MARCHF5 membrane associated ring-CH-type finger 5 -2.80866
COL6A3 collagen, type VI, alpha 3 -2.80058
MIS12 MIS12 kinetochore complex component -2.80009
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.7997
CDC37L1 cell division cycle 37-like 1 -2.79022
PPA2 pyrophosphatase (inorganic) 2 -2.78978
FAM216A family with sequence similarity 216, member A -2.78909
RBM14-RBM4 RBM14-RBM4 readthrough -2.78172
CREG1 cellular repressor of E1A-stimulated genes 1 -2.77869
WDR5B WD repeat domain 5B -2.77686
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.77422
CDCA4 cell division cycle associated 4 -2.7614
PLP1 proteolipid protein 1 -2.75613
RBBP4 retinoblastoma binding protein 4 -2.74972
RPP30 ribonuclease P/MRP 30kDa subunit -2.74844
TMEM168 transmembrane protein 168 -2.73172
MBIP MAP3K12 binding inhibitory protein 1 -2.7301
YTHDC1 YTH domain containing 1 -2.72023
ATP5PO ATP synthase peripheral stalk subunit OSCP -2.71946
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.7148
BRIX1 BRX1, biogenesis of ribosomes -2.71304
UBA3 ubiquitin-like modifier activating enzyme 3 -2.71102
RFC3 replication factor C (activator 1) 3, 38kDa -2.70404
PUM2 pumilio RNA-binding family member 2 -2.70237
DARS1 aspartyl-tRNA synthetase 1 -2.69878
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -2.69709
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.69448
PALS1 protein associated with LIN7 1, MAGUK p55 family member -2.69427
RBM39 RNA binding motif protein 39 -2.68787
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.67835
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.66852
TMEM106B transmembrane protein 106B -2.66612
MRPL39 mitochondrial ribosomal protein L39 -2.6656
SNRPG small nuclear ribonucleoprotein polypeptide G -2.65481
PSIP1 PC4 and SFRS1 interacting protein 1 -2.65421
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.6504
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -2.64644
CD164 CD164 molecule, sialomucin -2.64561
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -2.64155
CBX3 chromobox homolog 3 -2.63854
MAT2B methionine adenosyltransferase II, beta -2.63735
MAGT1 magnesium transporter 1 -2.6338
MPV17 MpV17 mitochondrial inner membrane protein -2.63143
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.63126
TBP TATA box binding protein -2.63054
PDHB pyruvate dehydrogenase (lipoamide) beta -2.63053
CRIPT cysteine-rich PDZ-binding protein -2.62492
ARID4B AT rich interactive domain 4B (RBP1-like) -2.61604
PBK PDZ binding kinase -2.61488
CRYZ crystallin, zeta (quinone reductase) -2.61341
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.59862
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.59446
FBXO5 F-box protein 5 -2.58736
MRPS22 mitochondrial ribosomal protein S22 -2.58481
RBM7 RNA binding motif protein 7 -2.5843
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -2.58319
TMEM267 transmembrane protein 267 -2.58185
CCNF cyclin F -2.58088
TP53 tumor protein p53 -2.57986
GEMIN2 gem (nuclear organelle) associated protein 2 -2.56973
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.56444
CETN3 centrin, EF-hand protein, 3 -2.56436
SELENOF selenoprotein F -2.55838
TMEM38B transmembrane protein 38B -2.5579
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.55374
MIS18A MIS18 kinetochore protein A -2.55186
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.54997
RPS25 ribosomal protein S25 -2.5364
HDAC2 histone deacetylase 2 -2.53335
HDDC2 HD domain containing 2 -2.53129
NUP43 nucleoporin 43kDa -2.52894
EML4 echinoderm microtubule associated protein like 4 -2.5269
NLRP2B NLR family pyrin domain containing 2B -2.52559
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.52415
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.52301
DNM1 dynamin 1 -2.51779
DET1 de-etiolated homolog 1 (Arabidopsis) -2.50513
CENPA centromere protein A -2.50245
PARP2 poly (ADP-ribose) polymerase 2 -2.50145
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.5005
ZNF83 zinc finger protein 83 -2.49939
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.49932
NPR2 natriuretic peptide receptor 2 -2.49388
CYCS cytochrome c, somatic -2.49155
VTA1 vesicle (multivesicular body) trafficking 1 -2.48948
TFB2M transcription factor B2, mitochondrial -2.48448
COMMD10 COMM domain containing 10 -2.48307
ADNP activity-dependent neuroprotector homeobox -2.47288
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.4591
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.45533
DEPDC1 DEP domain containing 1 -2.45432
RABGGTB Rab geranylgeranyltransferase, beta subunit -2.4533
TEFM transcription elongation factor, mitochondrial -2.45184
ATP5PF ATP synthase peripheral stalk subunit F6 -2.44905
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 -2.44606
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -2.446
THTPA thiamine triphosphatase -2.44574
HLTF helicase-like transcription factor -2.44375
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.44057
CDC23 cell division cycle 23 -2.43912
HMGN1 high mobility group nucleosome binding domain 1 -2.43892
ASF1B anti-silencing function 1B histone chaperone -2.43679
NUP37 nucleoporin 37kDa -2.43317
CHEK2 checkpoint kinase 2 -2.43307
TM2D1 TM2 domain containing 1 -2.43091
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.42789
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.42541
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -2.41806
FASTKD3 FAST kinase domains 3 -2.41656
SOCS5 suppressor of cytokine signaling 5 -2.41606
HAUS4 HAUS augmin-like complex, subunit 4 -2.41146
PRELID3B PRELI domain containing 3B -2.40909
CDKN3 cyclin-dependent kinase inhibitor 3 -2.40834
YME1L1 YME1-like 1 ATPase -2.40249
ZNF143 zinc finger protein 143 -2.40195
ZBTB25 zinc finger and BTB domain containing 25 -2.40191
RABL3 RAB, member of RAS oncogene family-like 3 -2.40137
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.40024
GOLT1B golgi transport 1B -2.40014
CD81 CD81 molecule -2.39911
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.39721
TMEM258 transmembrane protein 258 -2.39105
HIKESHI heat shock protein nuclear import factor hikeshi -2.3889
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.38232
RNMT RNA (guanine-7-) methyltransferase -2.38187
MRPS30 mitochondrial ribosomal protein S30 -2.37584
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -2.36819
SLC25A46 solute carrier family 25, member 46 -2.36779
CDC42 cell division cycle 42 -2.36767
RCAN2 regulator of calcineurin 2 -2.36642
CIRBP cold inducible RNA binding protein -2.36327
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.36312
CAAP1 caspase activity and apoptosis inhibitor 1 -2.36005
NUP205 nucleoporin 205kDa -2.35381
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.35213
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -2.35174
CCNG1 cyclin G1 -2.3504
HOXA1 homeobox A1 -2.35003
CAMLG calcium modulating ligand -2.34811
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.34438
COG2 component of oligomeric golgi complex 2 -2.34382
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.33919
ANKRD17 ankyrin repeat domain 17 -2.3354
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.33461
PCLAF PCNA clamp associated factor -2.33432
SRSF3 serine/arginine-rich splicing factor 3 -2.33361
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.33356
WDR43 WD repeat domain 43 -2.33121
IFT46 intraflagellar transport 46 -2.32982
EXOSC8 exosome component 8 -2.321
HSPA14 heat shock 70kDa protein 14 -2.32088
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -2.32013
POT1 protection of telomeres 1 -2.31974
KIF11 kinesin family member 11 -2.31854
RACGAP1 Rac GTPase activating protein 1 -2.31732
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.31726
SKIC8 SKI8 subunit of superkiller complex -2.31099
LETMD1 LETM1 domain containing 1 -2.30962
YAF2 YY1 associated factor 2 -2.30698
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -2.30343
PRKCD protein kinase C, delta -2.30323
GTF2B general transcription factor IIB -2.30057
CAPRIN1 cell cycle associated protein 1 -2.29841
STX10 syntaxin 10 -2.29708
USP19 ubiquitin specific peptidase 19 -2.29616
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.29503
COL3A1 collagen, type III, alpha 1 -2.29487
UBA2 ubiquitin-like modifier activating enzyme 2 -2.29478
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.29396
COASY CoA synthase -2.29392
SRSF7 serine/arginine-rich splicing factor 7 -2.29169
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.28566
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.28379
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -2.28274
LIN7C lin-7 homolog C (C. elegans) -2.28152
SYPL1 synaptophysin-like 1 -2.28087
RLF rearranged L-myc fusion -2.28056
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.27733
MAT2A methionine adenosyltransferase II, alpha -2.2771
NDC1 NDC1 transmembrane nucleoporin -2.27642
SIX1 SIX homeobox 1 -2.27638
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.27526
PUS3 pseudouridylate synthase 3 -2.27423
TTC33 tetratricopeptide repeat domain 33 -2.27298
CZIB CXXC motif containing zinc binding protein -2.27296
ELAVL1 ELAV like RNA binding protein 1 -2.26967
NIT2 nitrilase family, member 2 -2.2632
MRPS18B mitochondrial ribosomal protein S18B -2.26176
TMEM260 transmembrane protein 260 -2.25819
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.2559
SF1 splicing factor 1 -2.25377
COX7B cytochrome c oxidase subunit VIIb -2.25373
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.25334
CUTC cutC copper transporter -2.25273
TXNL1 thioredoxin-like 1 -2.2515
PEX12 peroxisomal biogenesis factor 12 -2.25126
INTS13 integrator complex subunit 13 -2.24997
LOC102724023 ES1 protein homolog, mitochondrial -2.24585
METTL4 methyltransferase like 4 -2.24527
SYNGR3 synaptogyrin 3 -2.24455
COXFA4 cytochrome c oxidase associated subunit FA4 -2.24447
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.24407
SSBP1 single-stranded DNA binding protein 1, mitochondrial -2.2417
FNBP4 formin binding protein 4 -2.24075
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.23318
SLC16A4 solute carrier family 16, member 4 -2.23116
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.22949
BIRC5 baculoviral IAP repeat containing 5 -2.22351
DENND2D DENN/MADD domain containing 2D -2.22212
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.22183
SLC38A6 solute carrier family 38, member 6 -2.22131
ZNF175 zinc finger protein 175 -2.21684
ANAPC5 anaphase promoting complex subunit 5 -2.21234
XPO1 exportin 1 -2.21207
GRID1 glutamate receptor, ionotropic, delta 1 -2.21203
RSRP1 arginine/serine-rich protein 1 -2.21147
ANXA2 annexin A2 -2.20843
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.20725
EED embryonic ectoderm development -2.2048
EIF1B eukaryotic translation initiation factor 1B -2.2028
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.20183
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.20177
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.20171
CASQ2 calsequestrin 2 (cardiac muscle) -2.20153
COQ3 coenzyme Q3 methyltransferase -2.20087
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.20083
HAX1 HCLS1 associated protein X-1 -2.19804
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -2.19803
MCM3 minichromosome maintenance complex component 3 -2.19639
TIPRL TOR signaling pathway regulator -2.19329
DONSON downstream neighbor of SON -2.19223
TMEM14A transmembrane protein 14A -2.19144
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.18842
IL16 interleukin 16 -2.18435
SPRY2 sprouty homolog 2 (Drosophila) -2.18384
ENOPH1 enolase-phosphatase 1 -2.18187
PRMT3 protein arginine methyltransferase 3 -2.18004
PTTG1 pituitary tumor-transforming 1 -2.17804
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -2.17771
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.17709
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -2.17543
ZNF106 zinc finger protein 106 -2.17301
FKBP14 FK506 binding protein 14, 22 kDa -2.17025
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.1667
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.16628
FOXO3 forkhead box O3 -2.16626
AGMAT agmatine ureohydrolase (agmatinase) -2.16526
DCLRE1C DNA cross-link repair 1C -2.16377
SNX5 sorting nexin 5 -2.16364
EDNRB endothelin receptor type B -2.16351
SRSF10 serine/arginine-rich splicing factor 10 -2.16212
LOX lysyl oxidase -2.161
MATR3 matrin 3 -2.1609
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -2.16038
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.15729
THAP12 THAP domain containing 12 -2.15708
TP53RK TP53 regulating kinase -2.15669
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.15664
RPS3A ribosomal protein S3A -2.15542
CCNT1 cyclin T1 -2.15373
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.14687
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.14647
COL1A2 collagen, type I, alpha 2 -2.14596
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.14554
ATP5PB ATP synthase peripheral stalk-membrane subunit b -2.1442
SRP9 signal recognition particle 9kDa -2.14259
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -2.1407
TMEM126B transmembrane protein 126B -2.14014
ACP6 acid phosphatase 6, lysophosphatidic -2.14001
SMAD5 SMAD family member 5 -2.13807
RTRAF RNA transcription, translation and transport factor -2.137
ELP4 elongator acetyltransferase complex subunit 4 -2.13689
OIP5 Opa interacting protein 5 -2.13419
PER1 period circadian clock 1 -2.13367
SYT2 synaptotagmin II -2.13254
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.13188
ABT1 activator of basal transcription 1 -2.1313
CRY1 cryptochrome circadian clock 1 -2.13059
RWDD1 RWD domain containing 1 -2.12865
KRT76 keratin 76, type II -2.12828
PNRC2 proline-rich nuclear receptor coactivator 2 -2.12677
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -2.12636
AUH AU RNA binding protein/enoyl-CoA hydratase -2.12531
UNC119B unc-119 homolog B (C. elegans) -2.12505
LYRM9 LYR motif containing 9 -2.12466
CEP76 centrosomal protein 76kDa -2.12197
TTC17 tetratricopeptide repeat domain 17 -2.11993
BOLA1 bolA family member 1 -2.11977
MDFIC MyoD family inhibitor domain containing -2.11864
USP1 ubiquitin specific peptidase 1 -2.11694
ETV1 ets variant 1 -2.11367
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.11326
CGGBP1 CGG triplet repeat binding protein 1 -2.11289
VAMP4 vesicle-associated membrane protein 4 -2.11186
RPL27A ribosomal protein L27a -2.11146
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.11046
GPN3 GPN-loop GTPase 3 -2.10905
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.10769
ATP5F1C ATP synthase F1 subunit gamma -2.10201
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.09868
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.0971
CDK7 cyclin-dependent kinase 7 -2.09535
NEK9 NIMA-related kinase 9 -2.09329
NUP153 nucleoporin 153kDa -2.09306
TRIM6-TRIM34 TRIM6-TRIM34 readthrough -2.08903
RPL39L ribosomal protein L39-like -2.08814
PRDX3 peroxiredoxin 3 -2.08781
PRPF38B pre-mRNA processing factor 38B -2.08727
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.08532
LAGE3 L antigen family, member 3 -2.08397
RBM23 RNA binding motif protein 23 -2.08362
H2AZ1 H2A.Z variant histone 1 -2.08353
ASF1A anti-silencing function 1A histone chaperone -2.08337
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.08258
SELL selectin L -2.08013
RBMS3 RNA binding motif, single stranded interacting protein 3 -2.07869
MORC3 MORC family CW-type zinc finger 3 -2.078
MGST2 microsomal glutathione S-transferase 2 -2.07529
CKS1B CDC28 protein kinase regulatory subunit 1B -2.0752
HSDL2 hydroxysteroid dehydrogenase like 2 -2.0723
PRPF4 pre-mRNA processing factor 4 -2.07203
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.06981
TRAT1 T cell receptor associated transmembrane adaptor 1 -2.06772
CD320 CD320 molecule -2.06499
HEATR1 HEAT repeat containing 1 -2.06174
AP3M2 adaptor-related protein complex 3, mu 2 subunit -2.05894
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -2.05704
MRPL42 mitochondrial ribosomal protein L42 -2.05634
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.05585
LTN1 listerin E3 ubiquitin protein ligase 1 -2.05411
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.04818
TBC1D15 TBC1 domain family, member 15 -2.04796
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.04297
DDTL D-dopachrome tautomerase-like -2.04238
RRAGA Ras-related GTP binding A -2.04152
NEK2 NIMA-related kinase 2 -2.04085
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.04071
MYCBP MYC binding protein -2.03905
TMEM9B TMEM9 domain family, member B -2.03842
CKS2 CDC28 protein kinase regulatory subunit 2 -2.03788
NAT10 N-acetyltransferase 10 (GCN5-related) -2.03759
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.03732
ZBTB38 zinc finger and BTB domain containing 38 -2.03651
VAV3 vav 3 guanine nucleotide exchange factor -2.03606
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -2.03494
CLDN15 claudin 15 -2.03398
RHOA ras homolog family member A -2.03384
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -2.0335
CUL4B cullin 4B -2.03317
TMED2 transmembrane emp24 domain trafficking protein 2 -2.03245
MCM9 minichromosome maintenance complex component 9 -2.0276
RPS10 ribosomal protein S10 -2.02726
TMPO thymopoietin -2.02462
UIMC1 ubiquitin interaction motif containing 1 -2.0228
INTS12 integrator complex subunit 12 -2.02068
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.02031
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -2.01229
HNRNPK heterogeneous nuclear ribonucleoprotein K -2.01218
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.01194
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.00915
UNC50 unc-50 homolog (C. elegans) -2.00786
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -2.00741
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.00587
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.00387
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.00357
RSRC2 arginine/serine-rich coiled-coil 2 -2.00355
FHL5 four and a half LIM domains 5 -2.00022