CRCGN015_MCF10A.WT.HP_24H:K03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dichlorophenol 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

49 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 5.10142
STK10 serine/threonine kinase 10 4.08868
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.77454
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.06996
ADAT1 adenosine deaminase, tRNA-specific 1 3.02766
FIP1L1 factor interacting with PAPOLA and CPSF1 2.50529
ADCY7 adenylate cyclase 7 2.26095
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.16447
PRR11 proline rich 11 2.08588
ATP13A2 ATPase type 13A2 2.04261
VMP1 vacuole membrane protein 1 2.02118
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.00656

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -4.92334
TNIP1 TNFAIP3 interacting protein 1 -4.79773
HAT1 histone acetyltransferase 1 -4.61702
KIF20A kinesin family member 20A -4.49276
C2CD5 C2 calcium-dependent domain containing 5 -4.30936
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.11803
TKT transketolase -4.08985
S100A8 S100 calcium binding protein A8 -4.02207
KIF14 kinesin family member 14 -4.0159
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -3.00552
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -2.87915
NAMPT nicotinamide phosphoribosyltransferase -2.74838
LDHB lactate dehydrogenase B -2.71523
COG5 component of oligomeric golgi complex 5 -2.70655
BCAP29 B-cell receptor-associated protein 29 -2.68983
PMPCB peptidase (mitochondrial processing) beta -2.46078
DOCK4 dedicator of cytokinesis 4 -2.37052
SCN5A sodium channel, voltage gated, type V alpha subunit -2.22453
ATP11B ATPase, class VI, type 11B -2.18757
PODXL podocalyxin-like -2.18365
PLPP3 phospholipid phosphatase 3 -2.16671
MAOA monoamine oxidase A -2.15428
KIZ kizuna centrosomal protein -2.13338
NRCAM neuronal cell adhesion molecule -2.12386
CTSZ cathepsin Z -2.11133
PUS7 pseudouridylate synthase 7 (putative) -2.10726
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.09885
GLI1 GLI family zinc finger 1 -2.08667
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -2.08329
CXCL14 chemokine (C-X-C motif) ligand 14 -2.07917
SYK spleen tyrosine kinase -2.07916
ADORA2A adenosine A2a receptor -2.04199
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.04094
ATP5MF ATP synthase membrane subunit f -2.03424
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 -2.02039
S100A12 S100 calcium binding protein A12 -2.01561
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -2.0021