CRCGN015_MCF10A.WT.HP_24H:K14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aspirin 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:K14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FOS FBJ murine osteosarcoma viral oncogene homolog 5.11613
HBA1 hemoglobin, alpha 1 4.84267
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.74038
MSRA methionine sulfoxide reductase A 3.16378
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.76456
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.75574
KIF5C kinesin family member 5C 2.44903
DENND2D DENN/MADD domain containing 2D 2.19304

decreased expression

Symbol Name Standardized Value
MRPS2 mitochondrial ribosomal protein S2 -4.99858
PAEP progestagen-associated endometrial protein -3.79336
SCYL3 SCY1-like 3 (S. cerevisiae) -3.62086
PPP1R26 protein phosphatase 1, regulatory subunit 26 -3.16042
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.58119
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.51098
TENT4A terminal nucleotidyltransferase 4A -2.47571
PARVB parvin, beta -2.36204
HSPA8 heat shock 70kDa protein 8 -2.29778
CANT1 calcium activated nucleotidase 1 -2.19433
OXA1L oxidase (cytochrome c) assembly 1-like -2.13022
TRAPPC3 trafficking protein particle complex 3 -2.11642
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.08185
PNOC prepronociceptin -2.07868
UBAC1 UBA domain containing 1 -2.04781
PRR5 proline rich 5 (renal) -2.02515
FAM193A family with sequence similarity 193, member A -2.02275