CRCGN015_MCF10A.WT.HP_24H:K16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyraldehyde 101.79 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:K16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.20256
SPAG4 sperm associated antigen 4 3.49233
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 3.29627
CCL2 chemokine (C-C motif) ligand 2 3.17145
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.51602
HBA1 hemoglobin, alpha 1 2.43829
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.33423
TXNL4B thioredoxin-like 4B 2.25662
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.06556

decreased expression

Symbol Name Standardized Value
TES testin LIM domain protein -4.42993
COPS7A COP9 signalosome subunit 7A -3.75721
VAT1 vesicle amine transport 1 -3.69548
FASTKD5 FAST kinase domains 5 -3.4841
KIF14 kinesin family member 14 -3.01502
TM9SF2 transmembrane 9 superfamily member 2 -2.52055
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.44285
YME1L1 YME1-like 1 ATPase -2.36776
GDF15 growth differentiation factor 15 -2.17411
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.00219