CRCGN015_MCF10A.WT.HP_24H:K17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyraldehyde 33.93 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

32 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:K17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.66071
GPER1 G protein-coupled estrogen receptor 1 3.90894
PPARG peroxisome proliferator-activated receptor gamma 3.45002
WIF1 WNT inhibitory factor 1 3.07928
HBA1 hemoglobin, alpha 1 2.95705
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.6804
CCDC92 coiled-coil domain containing 92 2.49783
PRKCQ protein kinase C, theta 2.44969
SMIM40 small integral membrane protein 40 2.44644
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.42756
TXNL4B thioredoxin-like 4B 2.37191
MELK maternal embryonic leucine zipper kinase 2.34975
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.33786
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.2115
PLSCR3 phospholipid scramblase 3 2.18239
NFIL3 nuclear factor, interleukin 3 regulated 2.06501
GPATCH8 G patch domain containing 8 2.06184
ALG9 ALG9, alpha-1,2-mannosyltransferase 2.02422
MSRA methionine sulfoxide reductase A 2.00713

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -6.0795
CYCS cytochrome c, somatic -3.99725
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.35066
METTL1 methyltransferase like 1 -2.67131
PMM2 phosphomannomutase 2 -2.63812
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.63482
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -2.57118
MSMO1 methylsterol monooxygenase 1 -2.50904
MSTO1 misato 1, mitochondrial distribution and morphology regulator -2.19592
MFSD12 major facilitator superfamily domain containing 12 -2.1623
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -2.15361
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.14488
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -2.12331