| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | kynurenic-acid 103.62 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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105 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AXIN1 | axin 1 | 5.55322 |
| MAMLD1 | mastermind-like domain containing 1 | 4.31096 |
| E2F2 | E2F transcription factor 2 | 4.06791 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 4.05365 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 3.31882 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.27878 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 3.15847 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.9469 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.89352 |
| PARN | poly(A)-specific ribonuclease | 2.87096 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.74506 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.64562 |
| TBCA | tubulin folding cofactor A | 2.64323 |
| RPS8 | ribosomal protein S8 | 2.60103 |
| BCAN | brevican | 2.5651 |
| UNC119 | unc-119 homolog (C. elegans) | 2.55044 |
| SMCP | sperm mitochondria-associated cysteine-rich protein | 2.45519 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.43292 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 2.39964 |
| KRT81 | keratin 81, type II | 2.3969 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | 2.36571 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 | 2.30849 |
| LOC112694756 | uncharaterized LOC112694756 | 2.30189 |
| TSG101 | tumor susceptibility 101 | 2.27863 |
| SDF2 | stromal cell-derived factor 2 | 2.27247 |
| SPRR2B | small proline-rich protein 2B | 2.21907 |
| MRPL23 | mitochondrial ribosomal protein L23 | 2.2058 |
| GRAMD1B | GRAM domain containing 1B | 2.1942 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z | 2.1654 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 | 2.13852 |
| DENND2D | DENN/MADD domain containing 2D | 2.11953 |
| CD40LG | CD40 ligand | 2.11144 |
| COMP | cartilage oligomeric matrix protein | 2.09424 |
| TPSG1 | tryptase gamma 1 | 2.08658 |
| EIF1B | eukaryotic translation initiation factor 1B | 2.08004 |
| CRNN | cornulin | 2.07607 |
| GSTO1 | glutathione S-transferase omega 1 | 2.06389 |
| RPS25 | ribosomal protein S25 | 2.05943 |
| ZMYM1 | zinc finger, MYM-type 1 | 2.05791 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 2.05721 |
| PLK1 | polo-like kinase 1 | 2.05048 |
| EXOSC9 | exosome component 9 | 2.05036 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 2.03896 |
| RAP1A | RAP1A, member of RAS oncogene family | 2.03664 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 2.02953 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 2.02 |
| MRPL57 | mitochondrial ribosomal protein L57 | 2.01906 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) | 2.01774 |
| STAG2 | stromal antigen 2 | 2.01566 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFB3 | transforming growth factor, beta 3 | -4.95901 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -4.59102 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.49107 |
| DNM1L | dynamin 1-like | -4.42393 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -4.35495 |
| GOLT1B | golgi transport 1B | -4.28389 |
| PAEP | progestagen-associated endometrial protein | -3.8789 |
| MED21 | mediator complex subunit 21 | -3.54825 |
| TENT4A | terminal nucleotidyltransferase 4A | -3.42621 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.82786 |
| CAPRIN2 | caprin family member 2 | -2.82699 |
| RECQL | RecQ helicase-like | -2.82211 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -2.77038 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -2.7342 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -2.70566 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -2.67636 |
| ERGIC2 | ERGIC and golgi 2 | -2.63723 |
| INTS13 | integrator complex subunit 13 | -2.61457 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -2.573 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.51343 |
| MAN1B1 | mannosidase, alpha, class 1B, member 1 | -2.50969 |
| CANT1 | calcium activated nucleotidase 1 | -2.50917 |
| IPO8 | importin 8 | -2.46077 |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | -2.45898 |
| TMEM184B | transmembrane protein 184B | -2.44836 |
| ADAR | adenosine deaminase, RNA-specific | -2.42674 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.4035 |
| UBAC1 | UBA domain containing 1 | -2.39251 |
| RARS1 | arginyl-tRNA synthetase 1 | -2.37894 |
| CS | citrate synthase | -2.3235 |
| ATF5 | activating transcription factor 5 | -2.31919 |
| PRKD2 | protein kinase D2 | -2.31744 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -2.29599 |
| ASS1 | argininosuccinate synthase 1 | -2.2924 |
| TMEM43 | transmembrane protein 43 | -2.2877 |
| SNAI2 | snail family zinc finger 2 | -2.24768 |
| GOLT1A | golgi transport 1A | -2.19291 |
| NELFB | negative elongation factor complex member B | -2.16782 |
| SLC61A1 | solute carrier family 61 member 1 | -2.16561 |
| DDX47 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 | -2.15279 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -2.13453 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -2.13089 |
| CRTAP | cartilage associated protein | -2.1217 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -2.12103 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -2.10927 |
| LAMA2 | laminin, alpha 2 | -2.10389 |
| CCDC91 | coiled-coil domain containing 91 | -2.09833 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | -2.09832 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -2.09133 |
| RTCA | RNA 3'-terminal phosphate cyclase | -2.07085 |
| IFNGR1 | interferon gamma receptor 1 | -2.06978 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -2.05725 |
| HTATSF1 | HIV-1 Tat specific factor 1 | -2.05641 |
| KIAA0930 | KIAA0930 | -2.01122 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 | -2.00832 |
| SMAD1 | SMAD family member 1 | -2.00225 |
