CRCGN015_MCF10A.WT.HP_24H:K23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(2-chloroethyl) phosphate 33.43 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:K23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.34194
SYNE2 spectrin repeat containing, nuclear envelope 2 4.33624
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.60926
PKN1 protein kinase N1 3.11493
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.06533
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.98938
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.57844
AAMDC adipogenesis associated, Mth938 domain containing 2.52
MAGEF1 melanoma antigen family F1 2.39204
AXIN1 axin 1 2.28853
SNX11 sorting nexin 11 2.26086
DNASE1L3 deoxyribonuclease I-like 3 2.21201
MFSD6 major facilitator superfamily domain containing 6 2.20602
RSF1 remodeling and spacing factor 1 2.1762
LY75-CD302 LY75-CD302 readthrough 2.17383
FDXR ferredoxin reductase 2.13463
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.09248
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.06581
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.05866
CADM1 cell adhesion molecule 1 2.04094

decreased expression

Symbol Name Standardized Value
SLC35F2 solute carrier family 35, member F2 -4.63327
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.82516
HMG20B high mobility group 20B -3.66886
NRIP1 nuclear receptor interacting protein 1 -3.36145
RGS2 regulator of G-protein signaling 2 -3.03371
PSIP1 PC4 and SFRS1 interacting protein 1 -2.84515
VDAC1 voltage-dependent anion channel 1 -2.7542
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.73678
IFRD2 interferon-related developmental regulator 2 -2.72912
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.3071
MTERF3 mitochondrial transcription termination factor 3 -2.2762