CRCGN015_MCF10A.WT.HP_24H:K24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(2-chloroethyl) phosphate 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

27 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADRB2 adrenoceptor beta 2, surface 4.40141
SPAG4 sperm associated antigen 4 3.76675
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.46857
KIF5C kinesin family member 5C 3.06029
ANO10 anoctamin 10 3.04628
CENPE centromere protein E, 312kDa 2.66423
PDIA5 protein disulfide isomerase family A, member 5 2.44619
SESN1 sestrin 1 2.15912
VKORC1 vitamin K epoxide reductase complex, subunit 1 2.09543
ZNF638 zinc finger protein 638 2.06001
RBBP5 retinoblastoma binding protein 5 2.0327

decreased expression

Symbol Name Standardized Value
CYCS cytochrome c, somatic -4.26744
CDC20 cell division cycle 20 -4.19844
LYPLA1 lysophospholipase I -3.68264
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.49979
CANT1 calcium activated nucleotidase 1 -3.20197
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.08963
THAP11 THAP domain containing 11 -3.06353
LAP3 leucine aminopeptidase 3 -3.01628
STXBP2 syntaxin binding protein 2 -3.01306
PCCB propionyl CoA carboxylase, beta polypeptide -2.99546
MRPL15 mitochondrial ribosomal protein L15 -2.67963
CCNB1 cyclin B1 -2.27492
KDM3A lysine (K)-specific demethylase 3A -2.20788
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -2.15973
STAT1 signal transducer and activator of transcription 1, 91kDa -2.14633
KIFBP kinesin family binding protein -2.07691