CRCGN015_MCF10A.WT.HP_24H:L02 Gene Set
Genes
55 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
5.30339
|
|
RGS2
|
regulator of G-protein signaling 2
|
4.78684
|
|
MYLK
|
myosin light chain kinase
|
3.99661
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
3.93238
|
|
SLC1A4
|
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
|
2.77369
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.70267
|
|
STXBP1
|
syntaxin binding protein 1
|
2.53319
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
2.52387
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.50981
|
|
SERPINB7
|
serpin peptidase inhibitor, clade B (ovalbumin), member 7
|
2.3892
|
|
GSAP
|
gamma-secretase activating protein
|
2.35762
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.3303
|
|
HMOX1
|
heme oxygenase 1
|
2.31568
|
|
UCN
|
urocortin
|
2.29332
|
|
SESN1
|
sestrin 1
|
2.2744
|
|
ACTG2
|
actin, gamma 2, smooth muscle, enteric
|
2.24387
|
|
SATB1
|
SATB homeobox 1
|
2.23397
|
|
INTS9
|
integrator complex subunit 9
|
2.22975
|
|
MMP1
|
matrix metallopeptidase 1
|
2.19935
|
|
KAT6B
|
K(lysine) acetyltransferase 6B
|
2.10371
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.05922
|
|
MTX2
|
metaxin 2
|
2.05087
|
|
RAB38
|
RAB38, member RAS oncogene family
|
2.02584
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-5.9366
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.70987
|
|
KIF14
|
kinesin family member 14
|
-4.21481
|
|
DSG2
|
desmoglein 2
|
-4.2073
|
|
UBE2C
|
ubiquitin-conjugating enzyme E2C
|
-4.03393
|
|
CCNB2
|
cyclin B2
|
-3.60367
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
-3.41831
|
|
HMG20B
|
high mobility group 20B
|
-3.38853
|
|
LDHD
|
lactate dehydrogenase D
|
-3.35791
|
|
ASPM
|
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
|
-2.8847
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-2.84361
|
|
CDC20
|
cell division cycle 20
|
-2.75572
|
|
TOP2A
|
topoisomerase (DNA) II alpha 170kDa
|
-2.73379
|
|
LBR
|
lamin B receptor
|
-2.57601
|
|
LSM8
|
LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.53196
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.50044
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
-2.4834
|
|
MSN
|
moesin
|
-2.37205
|
|
DNAJC2
|
DnaJ (Hsp40) homolog, subfamily C, member 2
|
-2.36674
|
|
PLK1
|
polo-like kinase 1
|
-2.35669
|
|
MCM3
|
minichromosome maintenance complex component 3
|
-2.25349
|
|
CDO1
|
cysteine dioxygenase type 1
|
-2.17852
|
|
TKT
|
transketolase
|
-2.17588
|
|
NUSAP1
|
nucleolar and spindle associated protein 1
|
-2.16279
|
|
YKT6
|
YKT6 v-SNARE homolog (S. cerevisiae)
|
-2.11406
|
|
BID
|
BH3 interacting domain death agonist
|
-2.09605
|
|
CENPN
|
centromere protein N
|
-2.04588
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.04454
|
|
GFPT2
|
glutamine-fructose-6-phosphate transaminase 2
|
-2.03976
|
|
CBR3
|
carbonyl reductase 3
|
-2.02368
|
|
RBM12B
|
RNA binding motif protein 12B
|
-2.00805
|
|
NCAPD2
|
non-SMC condensin I complex, subunit D2
|
-2.004
|
