CRCGN015_MCF10A.WT.HP_24H:L03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aflatoxin-b1 10.7 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

31 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 7.15461
CDPF1 cysteine-rich, DPF motif domain containing 1 3.71495
FGFR4 fibroblast growth factor receptor 4 3.46718
LOC122526780 uncharacterized LOC122526780 3.44352
INTS3 integrator complex subunit 3 3.30748
SYK spleen tyrosine kinase 3.10195
GRB10 growth factor receptor-bound protein 10 3.08956
SESN1 sestrin 1 2.93836
RGS2 regulator of G-protein signaling 2 2.90124
DDB2 damage-specific DNA binding protein 2, 48kDa 2.51115
UGDH UDP-glucose 6-dehydrogenase 2.25278
TXNL4B thioredoxin-like 4B 2.23999
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.09213
MOK MOK protein kinase 2.07372
CHEK1 checkpoint kinase 1 2.01348

decreased expression

Symbol Name Standardized Value
ISOC1 isochorismatase domain containing 1 -3.47994
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.36443
CCNB1 cyclin B1 -3.36262
HMG20B high mobility group 20B -3.34787
TSPAN4 tetraspanin 4 -3.188
CANT1 calcium activated nucleotidase 1 -3.15274
PSRC1 proline/serine-rich coiled-coil 1 -2.79619
NPDC1 neural proliferation, differentiation and control, 1 -2.66475
S100A8 S100 calcium binding protein A8 -2.62558
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.49607
ATG3 autophagy related 3 -2.47494
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.37017
BASP1 brain abundant, membrane attached signal protein 1 -2.22735
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.12585
FAM234B family with sequence similarity 234 member B -2.11695
TM9SF2 transmembrane 9 superfamily member 2 -2.07423