CRCGN015_MCF10A.WT.HP_24H:L06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-phenyl-p-phenylenediamine.hcl 10.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

9 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 5.04339
EPHB2 EPH receptor B2 3.89264
TXNL4B thioredoxin-like 4B 2.05906

decreased expression

Symbol Name Standardized Value
IER3 immediate early response 3 -3.31216
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.79395
COPS7A COP9 signalosome subunit 7A -2.348
CANT1 calcium activated nucleotidase 1 -2.33503
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.25088
S100A8 S100 calcium binding protein A8 -2.11214