CRCGN015_MCF10A.WT.HP_24H:L07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description iq 95.81 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 3.52492
CCP110 centriolar coiled coil protein 110kDa 3.44741
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.28101
AGR2 anterior gradient 2 3.20783
CHN1 chimerin 1 2.72934
PRKCH protein kinase C, eta 2.6228
NOTCH1 notch 1 2.46013
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.45876
TRAF3 TNF receptor-associated factor 3 2.26426
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.24897
NKRF NFKB repressing factor 2.16958
ADAR adenosine deaminase, RNA-specific 2.09657
PIAS3 protein inhibitor of activated STAT, 3 2.02015

decreased expression

Symbol Name Standardized Value
ACOT9 acyl-CoA thioesterase 9 -4.96423
UFM1 ubiquitin-fold modifier 1 -4.74723
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.30423
PEAK1 pseudopodium-enriched atypical kinase 1 -2.57614
FAIM Fas apoptotic inhibitory molecule -2.56969
RIC8A RIC8 guanine nucleotide exchange factor A -2.55337
TRAPPC3 trafficking protein particle complex 3 -2.53456
ANXA2 annexin A2 -2.34769
LOC127933115 uncharacterized LOC127933115 -2.31547
MAP3K19 mitogen-activated protein kinase kinase kinase 19 -2.30051
CAPN2 calpain 2, (m/II) large subunit -2.28622
TSPAN4 tetraspanin 4 -2.25245
ATP11B ATPase, class VI, type 11B -2.24639
GDF5 growth differentiation factor 5 -2.24215
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.21165
PLCD1 phospholipase C, delta 1 -2.2016
GDF15 growth differentiation factor 15 -2.17842
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.12738
PKD2L1 polycystic kidney disease 2-like 1 -2.12653
ADI1 acireductone dioxygenase 1 -2.07874
CRTAP cartilage associated protein -2.07858
NNAT neuronatin -2.07637
COG2 component of oligomeric golgi complex 2 -2.07623
CTNNA3 catenin (cadherin-associated protein), alpha 3 -2.06127
CBX2 chromobox homolog 2 -2.0587