| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | iq 31.94 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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50 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COQ8A | coenzyme Q8A | 4.3299 |
| GATA2 | GATA binding protein 2 | 4.13896 |
| MAMLD1 | mastermind-like domain containing 1 | 4.0283 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 3.815 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.7222 |
| COMP | cartilage oligomeric matrix protein | 3.61529 |
| MSRA | methionine sulfoxide reductase A | 3.2252 |
| METRN | meteorin, glial cell differentiation regulator | 3.12935 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.05498 |
| HBA1 | hemoglobin, alpha 1 | 2.96377 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.93713 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 2.48576 |
| OLFML2B | olfactomedin-like 2B | 2.36118 |
| TBX2 | T-box 2 | 2.28925 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 2.25475 |
| AGR2 | anterior gradient 2 | 2.23843 |
| PRKCD | protein kinase C, delta | 2.22111 |
| FTO | fat mass and obesity associated | 2.13742 |
| WDR6 | WD repeat domain 6 | 2.10395 |
| MOK | MOK protein kinase | 2.06663 |
| MAPT | microtubule-associated protein tau | 2.0424 |
| PGM3 | phosphoglucomutase 3 | 2.02452 |
| GRN | granulin | 2.02371 |
| GPX7 | glutathione peroxidase 7 | 2.01033 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.99778 |
| STMN1 | stathmin 1 | -3.76312 |
| GDF15 | growth differentiation factor 15 | -3.6733 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.61381 |
| UBE3C | ubiquitin protein ligase E3C | -3.28113 |
| MTERF3 | mitochondrial transcription termination factor 3 | -3.1841 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -3.07298 |
| TKT | transketolase | -3.00286 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -2.51684 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.46625 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -2.42512 |
| SV2B | synaptic vesicle glycoprotein 2B | -2.38115 |
| SQSTM1 | sequestosome 1 | -2.33426 |
| GPATCH1 | G patch domain containing 1 | -2.28525 |
| OVGP1 | oviductal glycoprotein 1, 120kDa | -2.27882 |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | -2.23641 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -2.21178 |
| KLHDC2 | kelch domain containing 2 | -2.20054 |
| EMC3 | ER membrane protein complex subunit 3 | -2.19368 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -2.17652 |
| ACTL7A | actin-like 7A | -2.13665 |
| AKAP4 | A kinase (PRKA) anchor protein 4 | -2.10508 |
| TLE4 | transducin-like enhancer of split 4 | -2.07298 |
| ATP11B | ATPase, class VI, type 11B | -2.04463 |
| ATP10B | ATPase, class V, type 10B | -2.02937 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -2.00154 |