CRCGN015_MCF10A.WT.HP_24H:L10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description resorcinol 97.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.4401
ADGRE5 adhesion G protein-coupled receptor E5 3.95557
FKBP14 FK506 binding protein 14, 22 kDa 3.90321
SPAG4 sperm associated antigen 4 3.49599
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.34029
CNRIP1 cannabinoid receptor interacting protein 1 3.24829
PNKP polynucleotide kinase 3'-phosphatase 2.96467
PPARG peroxisome proliferator-activated receptor gamma 2.73461
CCL2 chemokine (C-C motif) ligand 2 2.66824
VGLL4 vestigial-like family member 4 2.66207
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.46565
GET1 guided entry of tail-anchored proteins factor 1 2.45722
SATB1 SATB homeobox 1 2.35655
BACE2 beta-site APP-cleaving enzyme 2 2.34135
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.2157
COMP cartilage oligomeric matrix protein 2.18054
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.16152
PDIA5 protein disulfide isomerase family A, member 5 2.15288

decreased expression

Symbol Name Standardized Value
SCYL3 SCY1-like 3 (S. cerevisiae) -4.36356
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.97952
CTNND1 catenin (cadherin-associated protein), delta 1 -3.52318
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.41931
ARID4B AT rich interactive domain 4B (RBP1-like) -3.22815
TENT4A terminal nucleotidyltransferase 4A -3.08269
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.05855
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.89502
SGK1 serum/glucocorticoid regulated kinase 1 -2.68983
GNAS GNAS complex locus -2.52294
CCNB1 cyclin B1 -2.49497
WDR26 WD repeat domain 26 -2.32924
LYPLA1 lysophospholipase I -2.25102
STXBP2 syntaxin binding protein 2 -2.18381
TRIB3 tribbles pseudokinase 3 -2.11455
RCAN3 RCAN family member 3 -2.10846
GDF15 growth differentiation factor 15 -2.10442
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 -2.04256
CORO1A coronin, actin binding protein, 1A -2.02245
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.0224
ZNF354A zinc finger protein 354A -2.0138