CRCGN015_MCF10A.WT.HP_24H:L11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description resorcinol 32.43 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

44 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 5.14482
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.05573
TBX2 T-box 2 3.5019
AGR2 anterior gradient 2 3.27972
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.89822
FZD7 frizzled class receptor 7 2.78473
IGF1R insulin-like growth factor 1 receptor 2.75891
TXNL4B thioredoxin-like 4B 2.61928
GSTZ1 glutathione S-transferase zeta 1 2.61019
NPM3 nucleophosmin/nucleoplasmin 3 2.52432
EVL Enah/Vasp-like 2.2864
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.25285
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.19489
TPD52L2 tumor protein D52-like 2 2.18224
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.17587
KLHL36 kelch-like family member 36 2.1114
PRSS2 protease, serine, 2 (trypsin 2) 2.05399
GNG10 guanine nucleotide binding protein (G protein), gamma 10 2.0165

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -4.67176
CYCS cytochrome c, somatic -4.64493
DSG2 desmoglein 2 -4.62387
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.62159
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.98416
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.98105
SCYL3 SCY1-like 3 (S. cerevisiae) -3.4671
CBR3 carbonyl reductase 3 -3.36348
MSN moesin -2.9073
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.83751
TMEM147 transmembrane protein 147 -2.7082
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.52617
CD81 CD81 molecule -2.47447
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.46068
GPX4 glutathione peroxidase 4 -2.38922
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -2.34504
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.28783
BANP BTG3 associated nuclear protein -2.25942
LOC107986346 mitochondrial import receptor subunit TOM7 homolog -2.22164
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.12583
GDF15 growth differentiation factor 15 -2.07416
CD52 CD52 molecule -2.06347
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.059
TRAF1 TNF receptor-associated factor 1 -2.02778
CYB5A cytochrome b5 type A (microsomal) -2.01345
TMEM260 transmembrane protein 260 -2.003